腹腔镜手术治疗穿孔性阑尾炎对机体炎症反应的影响  

Impact of laparoscopic surgery for perforated appendicitis on inflammatory response and immune function

作　　者：黄华俊[1] 陈满宇[1] 

机构地区：[1]襄阳市中心医院普外一科,湖北襄阳441021

出　　处：《临床急诊杂志》2015年第7期517-519,共3页Journal of Clinical Emergency

摘　　要：目的:探讨腹腔镜手术治疗穿孔性阑尾炎对机体炎症反应的影响,进一步评价腹腔镜手术的微创效果。方法:将2011-10-2013-06共171例穿孔性阑尾炎患者随机分为腹腔镜手术组(腹腔镜组,81例)和开腹手术组(开腹组,90例),比较2组患者围手术期外周血降钙素原(PCT)、C反应蛋白(CRP)变化情况。结果:术后第1天2组PCT、CRP均较术前显著升高(P<0.05)。术后第3天腹腔镜组PCT、CRP水平较术前比较差异无统计学意义(P>0.05)。术后第5天腹腔镜组PCT、CRP水平较术前显著降低(P<0.05),术后第5天开腹组PCT、CRP水平较术前差异无统计学意义(P>0.05)。术后开腹组PCT、CRP水平显著高于腹腔镜组(P<0.05)。结论:与开腹手术比较,腹腔镜手术治疗穿孔性阑尾炎能够有效降低术后机体炎症反应的程度和持续时间,具有功能学微创优势。Objective：Investigating the impact of laparoscopic surgery on inflammatory response,to further evaluate the minimally invasive effect of laparoscopic surgery.Method：171patients with perforated appendicitis were randomly divided into laparoscopic surgery group（LS group,n=81）and open surgery group（OS group,n=90）from October 2011 to June 2013.Procalcitonin（PCT）,C-reactive protein（CRP）of peripheral blood were assayed perioperatively.Result：The levels of PCT and CRP in both group were both significantly increased on the 1st day postoper-atively（P〈0.05）.PCT and CRP levels in LS group returned to the preoperative levels on the 3th day postoperatively.The levels of PCT and CRP in LS group were significantly decreased on the 5st day postoperatively（P〈0.05）.Postoperative levels of PCT and CRP in OS group were signif-icantly higher than those in the LS group（P〈0.05）.Conclusion：Compared with open surgery,laparoscopic surgery can effectively reduce the degree of inflammation and have functional minimally invasive advantage.

关 键 词：腹腔镜 穿孔性阑尾炎 炎症反应 

分 类 号：R743.3[医药卫生—神经病学与精神病学]