乳腺鳞状细胞癌4例临床病理分析  

Squamous cell carcinoma of the breast:a clinicopathologic analysis of four cases

作　　者：李晓霞[1] 赵丽华[1] 姬爱国 郭静[1] 袁传涛[1] 马洪军[1] 李岩[1] 张仁亚[1] 

机构地区：[1]济宁医学院附属医院病理科,山东济宁272029 [2]汶上县人民医院病理科,山东济宁272501

出　　处：《诊断病理学杂志》2015年第7期407-409,413,共4页Chinese Journal of Diagnostic Pathology

摘　　要：目的探讨乳腺鳞状细胞癌的临床病理特征及诊断和鉴别诊断。方法对4例乳腺鳞状细胞癌进行光镜观察并文献复习。结果乳腺鳞状细胞癌好发于中老年人,平均年龄53岁。大体表现多为囊实性;镜下肿瘤均由多边形大细胞构成不规则的实性团索,细胞核核仁明显,可见不同程度的角化,细胞间存在明显的细胞间桥。结论乳腺鳞状细胞癌罕见,需要与乳腺腺鳞癌、血管肉瘤和浸润性导管癌中的鳞状上皮化生等鉴别。Objective To discuss the clinical and pathological features of squamous cell carcinoma of the breast and to explore its diagnosis and differential diagnosis. Methods Four cases of squamous cell carcinoma of the breast were investigated under light microscope and the related literatures were reviewed. Results Squamous cell carcinoma of the breast often occured in the elderly,and the average age was 53 years. On gross examination,the tumors were cystic-solid and consisted of irregular solid cell nests. The tumor cells were large and polygonal. Prominent nucleoli and varying degree of keratinization were seen. There was an obvious intercellular bridge between cells. Conclusion Squamous cell carcinoma of the breast is rare,and needs to be distinguished from adenosquamous carcinoma,angiosarcoma,squamous metaplasia of infiltrating ductal carcinoma of the breast and others.

关 键 词：乳腺 鳞状细胞癌 临床病理 鉴别诊断 

分 类 号：R737.9[医药卫生—肿瘤]