贵州省龙里县成年布依族和汉族血脂异常分析  

Dyslipidemia in Buyi and Han population in Longli County Guizhou Province

作　　者：平波[1] 王斌[2] 余杨文[3] 董芬[2] 谢勋祥[1] 潘利[2] 王棵[2] 毛兴华[1] 王谊勋 杜月清[1] 许可[4] 庞兴龙 陈婷[4] 潘慧[4] 马瑾[4] 钟勇[4] 王定明[3] 单广良[2] 

机构地区：[1]贵州省龙里县疾病预防控制中心,贵州龙里551200 [2]中国医学科学院基础医学研究所北京协和医学院基础学院流行病与卫生统计学系,北京100005 [3]贵州省疾病预防控制中心,贵州贵阳550004 [4]中国医学科学院北京协和医学院北京协和医院,北京100730

出　　处：《基础医学与临床》2015年第8期1042-1048,共7页Basic and Clinical Medicine

基　　金：国家"十二五"科技支撑计划课题(2012BAI37B02)

摘　　要：目的了解贵州省龙里县布依族、汉族居民血脂特征，为制定其防治措施提供依据。方法采取多阶段抽样方法抽取县城龙山镇2个居委会、4个乡镇、4个行政村20～80岁身体健康的布依族、汉族2929名常住村民为调查对象，进行问卷调查和体格检查，并检测其血浆总胆固醇（TC）、三酰甘油（TG）、高密度脂蛋白胆固醇（HDL-C）及低密度脂蛋白胆固醇（LDL-C）。并按判断标准对血脂异常及肥胖状况进行分析。结果布依族、汉族居民血脂异常总患病率为25．9％，男性（31．1％）显著高于女性（22．O％）（P〈0．001），汉族患病率（34．O％）显著高于布依族（21．7％）（P〈0．001）；高TG血症患病率为16．4％，汉族（22．6％）显著高于布依族（13．2％）（P〈0．001）；高TC血症患病率为10．70％，布依族为9．8％，汉族为12．5％，汉族高于布依族（P〈0．05）；HDL-C血症患病率为5．8％，汉族（9．1％）显著高于布依族（4．2％）（P〈0．001）；LDL．C血症患病率为4．8％，汉族（6．O％）显著高于布依族（4．1％）（JP〈0．05）；45～59岁年龄段、肥胖、高血压是血脂异常的主要危险因素。结论龙里县布依族和汉族成人血脂异常以高TG、高TC血症为主。布依族和汉族高TG血症、高TC血症和高LDL—C血症患病率均高于2010年中国调查结果，血脂异常总患病率呈明显上升趋势。应重视45岁以上中年人群血脂异常的防治。Objective To characterize dyslipidemia in Buyi and Han residents in Longli County and to provide evi- dence for prevention strategies. Methods Stratified sampling was adopted to select 2 communities in Longshan and 4 villages from 4 towns. 2 929 healthy Buyi and Han residents with age between 20 to 80 years were enrolled in this study. Their serum total cholesterol （ TC）, triglyceride （ TG）, high-density lipid-cholesterol （ HDL-C）, and low- density hpid cholesterol （LDL-C） were tested. Results The prevalence of dyslipidemia was 25.9% （31.1% for men, 22. 0% for women, respectively）. It was higher in men than in women （P 〈0. 001 ）. Compared with Buyi people, the prevalence was significantly higher in Han people （34.0%） than in Buyi was only 21.73% （P 〈 0. 001 ）. The prevalence of high TG level was significantly higher in Han population （P 〈0. 001 ）, The prevalence of low HDL-C level was significantly higher in Han population （ P 〈 0. 001 ）, The prevalence of high LDL-C level was significantly higher in Han population （P 〈 0. 05）, Additionally, obesity and hypertension were main risk fac- tors for dyslipidemia among adults aged from 45 to 59 years. Conclusions High TG and hypercholesterolemia are main components of dyslipidemia in Buyi and Han adults in Longli County. The prevalences of high TG, high TC, and high LDL-C are all higher than the results of 2010 national survey. Obviously, the prevalence of dyslipidemia has been increased over time. It suggestes that attention should be paid for prevention and treatment of dyslipidemia in adults with age from 45 to 59 years.

关 键 词：汉族 布依族 血脂异常 

分 类 号：R589.2[医药卫生—内分泌]