缺血性脑血管病血清hs-CRP水平与MR弥散成像的相关性分析  

CORRELATION BETWEEN SERUM hs-CRP LEVELS AND MR IMAGING IN ISCHEMIC CEREBROVASCULAR PATIENTS

作　　者：关坚红[1] 余仲苟[1] 马玉姗[1] 

机构地区：[1]开平市中心医院,广东开平529300

出　　处：《现代医院》2015年第8期79-80,83,共3页Modern Hospitals

基　　金：江门市科技计划项目(编号:2013019)

摘　　要：目的：分析缺血性脑血管病患者血清 hs－CRP水平与 MR 弥散成像之间的关联性，以探究血清 hs－CRP水平在缺血性脑血管病患者发病早期诊断与预后评估中的应用价值。方法选取2013年5月∽2014年12月收治的300例缺血性脑血管病患者为研究对象，按照病症类型分为急性脑梗死组100例、非急性期脑梗死组140例以及短暂性脑缺血发作组60例。其中急性脑梗死组100例患者按照MR弥散成像资料又可细分为三个亚组，A组：腔梗组28例，B组：小面积梗塞组50例，C组：大面积梗塞组22例。另选取40例健康体检者作为对照组，比较各组间血清hs－CRP水平并与MR弥散成像做关联性分析。结果急性脑梗死组、短暂性脑缺血发作组血清hs－CRP水平与对照组相比较差异具有统计学意义（ p＜0.05）；根据SPSS Spearman相关性分析结果可知，血清hs－CRP水平与MR 弥散成像资料所显示的梗死面积具有直接的关联性。结论缺血性脑血管病患者血清hs－CRP水平随着MR弥散成像所显示的梗死面积增大而升高，损伤面积越大，相应的血清hs－CRP水平变化越剧烈。Objective To analyze the correlation between serum hs -CRP levels and MR Imaging in ischemic cerebrovascu-lar patients.To explore the hs -CRP serum levels in ischemic cerebrovascular patients incidence of early diagnosis and prognosis e-valuation application value.Methods 300 cases of ischemic cerebrovascular disease as the research object were selected from May 2013 to December 2014.The disease is classified into acute cerebral infarction group 100 cases, acute phase of cerebral infarction group 140 cases and transient ischemic attack 60 cases.Among 100 cases of patients with acute cerebral infarction group, in accord-ance with the MR Imaging data, they can be subdivided into three groups.Group A： lacunar infarction group 28 cases; Group B：small area of infarction group 50 cases and group C： large area of infarction group 22 cases.Another 40 healthy physical examination were selected as control group.The hs -CRP serum levels were made correlation analysis with MR Imaging.Results The acute cerebral infarction and transient ischemic attack group serum hs -CRP level difference compared with the control group with statisti-cal significance （p〈0.05）; The SPSS Spearman correlation analysis result shows that the hs -CRP serum levels and MR Imaging data shown in the infarction area and the body has a direct correlation .Conclusion The ischemic cerebrovascular disease patients se-rum hs-CRP level with MR Imaging have shown increased infarct size and raise.Damage area is bigger, and the corresponding serum hs-CRP levels changes more violently.

关 键 词：缺血性脑血管病 血清HS-CRP水平 MR弥散成像 

分 类 号：R743.31[医药卫生—神经病学与精神病学]