症状性颅内动脉狭窄支架成形术短中期疗效及安全性的研究  

The short and medium term efficacy and safety of symptomatic intracranial arterial stenosis stenting

作　　者：陈渊[1] 钟维章[1] 李吕力[1] 陈娟带[1] 李燕华[1] 范秉林[1] 李兰晴[1] 

机构地区：[1]广西壮族自治区人民医院神经内科,南宁530021

出　　处：《中国临床新医学》2015年第7期608-611,共4页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

基　　金：广西医疗卫生重点科研课题(编号:重2011115)

摘　　要：目的探索症状性颅内动脉狭窄支架成形术的短中期疗效及安全性。方法 64例症状性颅内动脉狭窄患者分为药物组38例和支架组26例。比较两组治疗前后的美国国立卒中量表(NIHSS)评分及日常生活能力(ADL)评分,治疗后随访3个月内不良临床事件(脑出血、脑梗死、死亡)的发生率。结果支架组治疗后的NIHSS评分及ADL评分优于药物组(P<0.05)。两组治疗后3个月内不良临床事件发生率差异无统计学意义(P>0.05)。结论支架成形术治疗症状性颅内动脉狭窄相对于单纯药物治疗是一种安全有效的方法,长期疗效还需进一步观察。Objective To explore the short and medium term efficacy and safety of symptomatic intracranial arterial stenosis stenting. Methods 64 patients with symptomatic intracranial arterial stenosis were treated with medication（ medication group,n = 38） or intracranial arterial stenting（ stent group,n = 26）. NIHSS（ US National Stroke Scale） scores and ADL（ activities of daily living） scores were compared between the two groups before and after the treatment. The rates of clinical events（ including cerebral hemorrhage,cerebral infarction and death） were also assessed and compared between the two groups with a follow-up of three months after the treatment. Results NIHSS scores and ADL scores were significantly higher in the stent group than those in the medication group（ P〈0. 05）.There is no significant difference in the rates of clinical events between the two groups（ P〈0. 05）. Conclusion Symptomatic intracranial arterial stenosis stenting is more safe and effective than medication for the treatment of symptomatic intracranial arterys tenting.

关 键 词：症状性颅内动脉狭窄 支架成形术 药物治疗 疗效 安全性 

分 类 号：R743[医药卫生—神经病学与精神病学]