慢性阻塞性肺疾病患者营养状态评价研究  

Study on the Nutrition Status in Patients with COPD

作　　者：刘广杰[1] 胥杰[1] 罗秀芳[1] 

机构地区：[1]首都医科大学附属北京同仁医院呼吸内科,100730

出　　处：《医学研究杂志》2015年第7期47-49,共3页Journal of Medical Research

基　　金：教育部留学回国人员科研启动基金资助项目(2005546)

摘　　要：目的探究慢性阻塞性肺疾病、慢性支气管炎患者营养状态的改变,探讨GOLD分组各组中慢性阻塞性肺疾病患者的营养状态。方法观察稳定期慢性阻塞性肺疾病患者40例,病情程度分别处于GOLD分组的A、B、C、D组,每组患者10例。另外选取慢性支气管炎患者20例,健康人对照20例。分别检测体重指数(BMI)、肱三头肌皮皱(TSF)、血浆白蛋白水平(ALB),评估其营养状态。结果慢性阻塞性肺疾病患者与健康对照组营养状态指标如下:BMI分别为21.3±4.0kg/m2和24.7±3.7kg/m2,差异有统计学意义(P<0.01);TSF分别为10.3±4.4mm和13.0±4.4mm,差异有统计学意义(P<0.05);ALB分别为34.4±5.3g/L和39.5±6.7g/L,差异有统计学意义(P<0.01);慢性阻塞性肺疾病患者依据GOLD分组为A、B、C、D组,依据肺功能将其分为A+B组、C+D组,两组检测指标BMI分别为22.1±3.5kg/m2和19.9±4.3kg/m2,差异有统计学意义(P<0.05);TSF分别为12.9±4.4mm和7.7±2.4mm,差异有统计学意义(P<0.01);ALB分别为36.5±5.4g/L和32.3±4.5g/L,差异有统计学意义(P<0.01);慢性支气管炎组BMI、TSF及ALB的检测指标与对照组相比,差异无统计学意义(P>0.01)。结论慢性阻塞性肺疾病患者的BMI、TSF、ALB较健康对照组显著降低,存在营养状态不良。GOLD分组中C组与D组的的营养状态较A组与B组差。在临床工作中,GOLD分组中C、D组患者需更加关注其营养状态并给予相应措施。Objective To investigate the parameters of nutrition status in the patients with COPD and study the difference nutrition status among COPD GOLD classification including A, B,C and D.Methods According to the global initiative for chronic obstructive lung disease （ GOLD） criteria, we classified the COPD outpatients into A, B, C, D group, with 10 cases in each group, 20 cases healthy people as control group as well as 20 patients with chronic bronchitis.Body mass index （ BMI） , triceps skin-fold thickness（ TSF） ,ser-um albumin （ ALB ） were measured in each person.Results BMI was significantly lower in COPD group than health control group （21.3 ±4.0kg/m^2 vs 24.7 ±3.7kg/m^2, P〈0.01） ; TSF was significantly reduced in COPD group than the control group （10.3 ± 4.4mm vs 13.0 ±4.4mm, P〈0.05）;ALB in COPD group was significant decreased than the control group （34.4 ±5.3g/L vs 39.5 ± 6.7g/L, P〈0.01）.Moreover, there were significantly differences in the nutrition status among COPD groups.BMI in the group of（C＋D） was significantly lower compared with the group of （A＋B） （19.9 ±4.3kg/m^2 vs 22.1 ±3.5kg/m^2, P〈0.05）.TSF was significant-ly decreased in the group of （C＋D） than the group of （A＋B）（7.7 ±2.4mm vs 12.9 ±4.4mm, P〈0.01）.Compared with the group of （A＋B）, ALB was also significantly reduced in the group of （C＋D）（32.3 ±4.5g/L vs 36.5 ±5.4g/L, P〈0.01）.Conclusion The parameters of BMI, TSF, ALB are significantly reduced in the patients with COPD.Severe COPD easily develops malnutrition.Ac-cording to COPD GOLD classification, the nutrition status is worse in the group of （ C＋D） than in the group of （ A＋B） .It is worthy to pay attention to the nutrition status of COPD patients, and give appreciate therapy for patients with COPD.

关 键 词：慢性阻塞性肺疾病 GOLD分组 营养 

分 类 号：R563[医药卫生—呼吸系统]