儿童重症肺炎血浆生长抑素水平变化临床分析  

The Clinical Analysis of the Blood Level Changes of Somatostatin in Children With Severe Pneumonia

作　　者：李晓莉[1] 王凤枝[1] 

机构地区：[1]漯河医学高等专科学校三附院,462002

出　　处：《中国继续医学教育》2015年第20期49-51,共3页China Continuing Medical Education

摘　　要：目的研究儿童重症肺炎生长抑素(SST)水平的变化及意义。方法采用放射免疫分析方法,检测并比较重症肺炎组和普通肺炎组、对照组血浆SST水平,观察重症肺炎患儿治疗前后血浆SST水平变化,分析SST水平与Pa O2的相关性。结果重症肺炎组患儿血浆SST水平较普通肺炎组和对照组降低(t分别为2.79、7.05,P均<0.01),治疗后血浆SST水平较前升高(t=4.59,P<0.01),差异具有统计学意义。重症肺炎患儿血浆SST水平与Pa O2呈正相关(r=0.586,P<0.05)。结论检测血浆SST水平有助于了解重症肺炎患儿病情变化,指导治疗。Objective To study the significance of blood level changes of somatostatin （SST） in children with severe pneumonia. Methods In order to observe the changes of blood level of SST in children with severe pneumonia between pre and post treatment and to analyze the correlation of the blood level of SST and PaO2, radioimmunoassay method was adopted to detect and compare the blood level of somatostatin in children with severe pneumonia, children with common pneumonia and healthy children （control group）. Results There is a statistical significance among the three groups that on the one hand, the blood levels of SST in severe pneumonia group were objectively lower than common pneumonia group and control group （t=2.79, 7.05, P〈0.01）, on the other hand, the blood level of SST in severe pneumonia group increased after the treatment （t=4.59, P〈0.01）. In addition, the blood levels of SST in severe pneuminia group were positively correlated with PaO.~ （r-=0.586, P〈0.05）. Conclusion It is helpful to investigate the condition changes of children with severe pneumonia and guiding their treatments by detecting the blood level of SST.

关 键 词：重症肺炎 生长抑素 病情变化 儿童 

分 类 号：R735[医药卫生—肿瘤]