动脉热灌注化疗栓塞治疗术后多灶性复发性原发性肝癌  

Liver cancer of multifocal recurrent primary after Heat artery perfusion chemotherapy embolization treatment postoperative

作　　者：王振军[1] 胡鸿涛[1] 黎海亮[1] 郭晨阳[1] 骆俊朋[1] 

机构地区：[1]郑州大学附属肿瘤医院/河南省肿瘤医院放射介入科,河南郑州450003

出　　处：《医药前沿》2015年第18期23-25,共3页Journal of Frontiers of Medicine

摘　　要：目的：探讨动脉热灌注化疗栓塞治疗术后多灶性复发的原发性肝癌的临床疗效。方法：对48例原发性肝癌行根治性切除术后出现多灶性肝内复发的患者行动脉热灌注加动脉化疗栓塞治疗，统计患者治疗前后肝肾功能变化、治疗有效率及患者生存期。结果48例患者中客观．有效率（CR＋PR）为75％（36／48），共总有效率（CR＋PR＋SD）为87．556（42／48）。中位生存时间为18．0个月（9556置信区间[CI]为16—24个月），无严重毒副反应发生。结论经肝动脉热灌注化疗栓塞治疗术后多灶性复发的原发性肝癌可明显延长患者生存期，减少介入诊疗次数。Objective To explore the clinical effect of Liver cancer of multifocal recurrent primary after Heat artery perfusion chemotherapy embolization treatment postoperative. Methods Choose 48 cases of primary liver cancer do hot perfusion and artery embolization chemotherapy, the patients are multifocal intrahepatic recurrence after radical resection. Statistics the change of patients of liver and kidney function before and after treatment, treatment efficiency, and patient survival. Results In 48 cases patients, efficient [CR ＋ PR） was 75% （36/48）, the total effective rate [CR ＋ PR ＋ SD） was 87.5% [42/48）. Median survival time was 18.0 months （95% confidence interval [CI] for 16 to 24 months）, no serious adverse reaction. Conclusion Using the method of trans-arterial thermochemotherapy infusion combined with TACE to treat the patients with multiple intrahepatic hepatocellular carcinomas can prolong the survival time of patients and decrease the frequency of treatment.

关 键 词：动脉热灌注 化疗栓塞 多灶性复发性肝癌 

分 类 号：R730.5[医药卫生—肿瘤]