淋巴瘤并发静脉血栓11例临床分析  

Lymphoma with venous thromboembolism in 11 cases

作　　者：刘艳慧[1,2] 薛飞[1,2] 杨靖[1,2] 张茵[1,2] 雷平冲[1,2] 朱尊民[1,2] 孙恺[1,2] 翟亚平[1,2] 

机构地区：[1]郑州大学人民医院 [2]河南省人民医院血液科,郑州450003

出　　处：《中华实用诊断与治疗杂志》2015年第8期796-797,共2页Journal of Chinese Practical Diagnosis and Therapy

基　　金：国家自然科学基金(81273260);郑州市科技局基金(131PPTGG379-1)

摘　　要：目的探讨淋巴瘤合并静脉血栓（venous thromboembolisru，VTE）的临床特征。方法回顾性分析11例成人淋巴瘤合并VTE患者临床资料。结果11例淋巴瘤并VTE患者中，2例为霍奇金淋巴瘤，9例为非霍奇金淋巴瘤；3例以VTE为首发症状，7例于化疗第2∽3周期诊断VTE，1例确诊淋巴瘤2a后使用沙利度胺治疗期间发生VTE；肢体VTE8例（其中1例为中心静脉置管相关性血栓），上腔静脉综合征2例，急性肺动脉栓塞1例。结论VTE可能是淋巴瘤的首要表现，化疗及深静脉置管等是淋巴瘤并发血栓的重要诱因。Objective To investigate the clinical features of lymphoma with venous thromboembolism （VTE）. Methods The clinical data of 11 cases of lymphoma with VTE were retrospectively analyzed. Results In 11 cases of lymphoma with VTE, there were 2 cases of Hodgkin＇s lymphoma （HL） and 9 cases of non-HL. VTE was the initial symptom in 3 cases, occurred in the second or third cycle of chemotherapy in 7, and occurred during the treatment with thalidomide 2 years after the diagnosis of lymphoma. VTE occurred on the limbs in 8 cases including 1 case of central venous catheter related VTE, superior vena cava syndrome in 2 cases, and acute pulmonary embolism in 1. Conclusion VTE could be the initial manifestation of lymphoma, and chemotherapy and central venous catheter are the important risk factors for VTE in lymphoma.

关 键 词：淋巴瘤 静脉血栓栓塞 临床特征 

分 类 号：R733.1[医药卫生—肿瘤]