高血压脑出血早期控制血压对血肿扩大的影响  

Influence of early intensively antihypertensive treatment on hematoma enlargement in patients with hypertensive cerebral hemorrhage

作　　者：江思德[1] 邹耀兵 唐明山[1] 肖静[1] 潘成德[1] 

机构地区：[1]重庆市巴南区人民医院神经内科,401320

出　　处：《重庆医学》2015年第23期3216-3217,3220,共3页Chongqing medicine

基　　金：重庆市医疗特色专科建设项目经费资助[渝卫科教(2010)52号]

摘　　要：目的研究早期控制血压对高血压性脑出血患者血肿扩大的影响。方法对96例急性期高血压脑出血患者随机分为强化降压组(48例)和标准降压组(48例),分别予以强化降压及标准降压。两组入院时及入院24h查头颅CT及神经功能评分,然后对两组头颅CT血肿体积大小及神经缺损功能评分进行对比分析。结果入院后24h强化降压组较标准降压组神经功能评分明显降低(P<0.05),入院后24h复查头部CT发现,强化降压组和标准降压组入院24h血肿体积及血肿扩大发生率比较,差异有统计学意义(P<0.05)。结论高血压脑出血早期控制血压可降低血肿扩大,减少神经功能缺损症状。Objective To investigate the effect of blood pressure control for early enlargement of hypertensive intracerebral hemorrhage.Methods A total of 96 patients were divided randomly into intensive blood pressure lowering group（n=48）and standard antihypertensive group（n=48）.Patients were checked head CT and was evaluated defect of nerve function score immediately when they arrive at hospital and after 24 hours.Then the clinical curative effect was evaluated.Results The defect of nerve function score in intensive blood pressure lowering group was lower than that of the standard antihypertensive group（P〈0.05）.The hematomas volume within 24 hours of admission and the rate of hematoma enlargement of intensive blood pressure lowering group were sharply smaller than those of standard antihypertensive group（P〈0.05）.Conclusion Controlling blood pressure actively could decrease ratio early enlargement of hematoma and defect of nerve function score in patients with hypertensive cerebral hemorrhage.

关 键 词：颅内出血 高血压性 血肿 血液凝固 血肿扩大 

分 类 号：R743.34[医药卫生—神经病学与精神病学] R544.1[医药卫生—临床医学]