两种药物联合应用在精神分裂症患者手术麻醉中的疗效分析  

Analysis on effect of combined application of two drugs in operative anesthesia of schizophrenic patients

作　　者：何琼珍[1] 王富芬 李智[1] 

机构地区：[1]四川省广元市精神卫生中心麻醉科,628001

出　　处：《检验医学与临床》2015年第15期2220-2221,共2页Laboratory Medicine and Clinic

摘　　要：目的探讨雷米芬太尼联合丙泊酚在精神分裂症患者手术麻醉中的疗效。方法选取2012年9月至2014年9月于广元市精神卫生中心行手术治疗的精神分裂症患者120例,根据麻醉用药的不同,随机分为观察组和对照组各60例,观察组采用雷米芬太尼联合丙泊酚进行麻醉,对照组采用芬太尼联合丙泊酚进行麻醉,观察2组患者麻醉期间血压、心率、麻醉后恢复情况。结果观察组在麻醉期间血压及心率比对照组明显降低,差异有统计学意义(P<0.05);插管及切皮后的血压及心率明显低于对照组,差异有统计学意义(P<0.05);手术结束后,观察组的心率增加明显高于对照组,差异有统计学意义(P<0.05);观察组手术后的恢复情况快于对照组,差异有统计学意义(P<0.05)。结论采用雷米芬太尼联合丙泊酚进行麻醉处理,可以使精神分裂症患者手术更安全;雷米芬太尼联合丙泊酚更适合应用于精神分裂症患者的手术。Objective To study the application effect of remifentanil combined with propofol in operative anes‐thesia of schizophrenic patients .Methods 120 schizophrenic patients with surgical treatment in our hospital from September 2012 to September 2014 were selected and randomly divided into the observation group（n = 60） and the control group（n= 60） according to different anesthetic drugs .The observation group adopted the remifentanil com‐bined with propofol anesthesia ,while the control group adopted the fentanyl combined with propofol anesthesia .The blood pressure ,heart rate and recovery situation after anesthesia were observed in the two groups .Results The blood pressure and heart rate during anesthesia in the observation group were significantly reduced ,which were sig‐nificantly lower than those in the control group ,the differences were statistically significant（P 〈 0 .05） ;Blood pres‐sure and heart rate after intubation and skin incision in the observation group were significantly lower than those in the control group with statistical differences（P〈 0 .05） ;The heart rate increase after surgery in the observation group was significantly higher than that in the control group with statistical significance（P〈 0 .05） ;The recovery situation after surgery in the observation group was more rapid than that in the control group with statistical significance（P〈0 .05） .Conclusion Adopting remifentanil combined with propofol anesthesia can safely conduct the operation in the patients with schizophrenia ,therefore which is more suitable for opearion in schizophrenic patients .

关 键 词：精神分裂症患者 手术麻醉 雷米芬太尼 丙泊酚 

分 类 号：R749.3[医药卫生—神经病学与精神病学]