256层螺旋CT全肝灌注成像对正常肝脏血流状态的评价研究  

Evaluation of the blood flow in normal liver by 256 Slices MSCT whole liver perfusion imaging

作　　者：高知玲[1] 李梦迪[2] 朱凯[1] 陈勇[1] 

机构地区：[1]宁夏医科大学,宁夏银川750004 [2]宁夏医科大学总医院放射科,宁夏银川750004

出　　处：《宁夏医学杂志》2015年第8期678-680,共3页Ningxia Medical Journal

基　　金：国家自然科学基金资助项目(61061005)

摘　　要：目的通过多层螺旋CT全肝灌注模式,探讨正常肝脏各段血流状态。方法选择胃癌患者43例,男28例,女15例;年龄35~81岁,中位年龄为55.6岁;应用多层螺旋CT（MSCT）进行全肝灌注增强扫描,并分别测定肝脏各段灌注参数值,包括动脉灌注量（HAP）、门静脉灌注量（PVP）、总肝灌注量（TLP）和肝动脉灌注指数（HPI）,以评价正常肝脏各段的血流动力学状态。结果正常肝脏S3段HAP与S6、S7、S8以及S4与S7段差异均有统计学意义（P〈0.05）,S3段HPI与S7段差异亦有统计学意义（P〈0.05）。不同性别正常肝脏Couinaud 8段之间灌注参数值差异无统计学意义。结论正常肝脏部分肝段之间血流存在差异,多螺旋CT全肝脏灌注成像能更全面地评价肝脏的血流状态。Objective To investigate the blood flow characteristics of normal hepatic segments by the pattern of whole liver per- fusion with Multi - slice spiral computed tomography （MSCT）. Methods 43 patients with gastric cancer were examined with whole liver perfusion enhanced CT scans investigations for detecting gastric cancer （male： 28 cases, female： 15 cases; age： 35 ~ 81 yrs, mean age 55.6 yrs）. Four kinds of perfusion parameters （ HAP, PVP, TLP and HPI） of Couinaud＇ s segments were measured for estimating blood - dynamics condition. Results The hepatic arterial perfusion（HAP） in segment 3 was significantly higher than in segment 6,7,8 （P 〈 0.05 ）, and the HAP in segment 4 was significantly higher than in segment 7 （ P 〈 0.05 ）, the hepatic perfusion index （HPI） in segment 3 was significantly higher than in segment 7 （P 〈 0.05）. No significant correlation was found between genders. Conclusion Our results suggest that differences exist in normal hepatic parenchyma between hepatic segments. MSCT whole liver perfusion imaging can more comprehensively evaluate the blood flow in liver.

关 键 词：CT灌注成像 肝脏 血流动力学 

分 类 号：R735.2[医药卫生—肿瘤]