副肿瘤性边缘叶脑炎的临床及MRI特征  

The MR features of paraneoplastic limbic Encephalitis

作　　者：李明全[1] 娄晓宇[1] 苗宝娟[1] 

机构地区：[1]漯河市中心医院(漯河医专第一附属医院)医学影像科,河南462000

出　　处：《放射学实践》2015年第8期802-805,共4页Radiologic Practice

摘　　要：目的:探讨副肿瘤性边缘叶脑炎(PLE)的MRI特征。方法:回顾性分析8例经临床诊断治疗的PLE的临床及MRI资料。所有患者均行常规MRI平扫及DWI检查,其中6例行增强扫描。结果:18例病变分布均以海马及海马旁回为主,其中3例可见病变同时累及双侧杏仁核、2例累及双侧扣带回、1例累及左侧岛叶、1例累及桥脑。病变双侧对称分布7例,单侧发病1例。2信号特征:6例病变于T1WI上呈较均匀稍低信号,T2WI呈高信号,DWI呈稍高或等信号;2例于T1WI呈等信号,T2WI呈稍高信号,DWI呈等信号;所有病灶在FLAIR图像上均呈高信号。6例行增强扫描,5例病变无强化,1例可见小片状轻度强化。结论:PLE具有较典型的临床及MRI特征,应结合抗体检测及其它全身检查,积极寻找原发肿瘤进行综合治疗。Objective：To investigate the MR features of paraneoplastic limbic encephalitis （PLE）.Methods：The clini-cal and MRI data of 8 cases with PLE were retrospectively analyzed.All patients underwent plain MRI and DWI scan,6 of them also underwent post-contrast MRI study.Results：①Hippocampus and parahippocampal gyrus were involved in all ca-ses,the bilateral amygdala was also involved in 3 cases,the bilateral cingulate gyri in 2 cases,the left insula in one case and the pons in one case.The lesions distributed bilateral symmetrically in 7 cases,unilateral in one case.②MRI signal changes：prolonged T1 and T2 signal,or restricted diffusion on DWI in 6 cases,isointensity on T1 WI and DWI,slight hyperintensity on FLAIR images.Six cases underwent post-contrast MRI study,only one case had mild enhancement.Conclusion：PLE had typical MRI characteristics,we should combine antibody testing and other systemic examinations,to seek the primary tumor and treat it comprehensively.

关 键 词：边缘叶脑炎 副肿瘤综合征 临床特征 磁共振成像 

分 类 号：R739.4[医药卫生—肿瘤]