淮安地区食管癌患者ABO血型的相关性研究  

The relationship between ABO blood type and esophageal cancer in Huaian China

作　　者：陈星[1] 刘帅帅[2,3,4] 李前文[4] 

机构地区：[1]界首市人民医院,安徽界首236500 [2]蚌埠医学院,安徽蚌埠233000 [3]解放军第82医院肿瘤科,江苏淮安223001 [4]枣庄市立医院,山东枣庄277100

出　　处：《现代肿瘤医学》2015年第18期2604-2605,共2页Journal of Modern Oncology

基　　金：国家高科技研究发展计划(863计划)(编号:2014AA020901);南京军区医学科技创新课题(编号:08MA036)

摘　　要：目的:调查淮安市食管癌患者ABO血型分布特点,分析其相关性并探讨各种血型物质在食管癌发生中的作用。方法:收集我院初治的食管癌患者263例为病例组,随机抽取淮安市中心血站同时期1000例健康献血人群ABO血型资料为对照组。统计分析两组ABO血型分布频率,进行相关性分析和血型的相对危险率分析。结果:病例组A型血占27.4%,对照组为17.8%,A型血频率在病例组与对照组之间存在显著性差异。病例组B型血、O型血和AB型血型分别占31.6%、30.0%、11.0%,对照组分别占35.7%、36.2%、10.3%,均无显著性差异。相对危险率A型血者为1.54,B型血者为0.89,O型血者为0.83,AB型血者为1.06。结论:淮安ABO血型分布与食管癌的发生具有一定的关系,提示血型物质A抗原可能是食管癌的一个危险因子。Objective：To investigate ABO blood group distribution characteristics of patients with esophageal cancer in Huaian China.Methods：To select 263 patients with esophageal cancer in Huaian as the case group,1000 cases of healthy blood donors in Huaian blood center during the same period as control group.Results：In case group, type A blood occupied 27 .4 %,1 7 .8 % in the placebo group （P 〈0.05）.For B,O and AB blood group,there were 31.6%,30.0%,11.0% in case group,and in control group there were 35.7%,36.2%,10.3%（P 〉0.05）. Relative risk type A was 1.54,type B was 0.89,type O was 0.83,AB was 1.06.Conclusion：The ABO blood group distribution and esophageal cancer has some correlation.Blood group antigen A is an important risk factor for esopha-geal cancer.

关 键 词：ABO血型 食管癌 危险因子 

分 类 号：R735.1[医药卫生—肿瘤]