营养干预对宫颈癌患者同步放化疗耐受性及生活质量的影响  

Effect of nutritional intervention on tolerance and quality of life in cervical cancer patients receiving concurrent chemoradiotherapy

作　　者：张珺[1] 杨金香[2] 王峻峰[2] 严芳[2] 殷铁军[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院综合科,湖北武汉430030 [2]华中科技大学同济医学院附属同济医院肿瘤放疗中心,湖北武汉430030

出　　处：《现代肿瘤医学》2015年第18期2652-2654,共3页Journal of Modern Oncology

基　　金：湖北省人口和计划生育委员会科研基金资助(编号:JS-20130019)

摘　　要：目的:探讨营养干预对宫颈癌患者同步放化疗耐受性及生活质量(QOL)的影响。方法:将86例宫颈癌患者随机分为营养干预组和对照组,观察两组患者的放疗中断率、化疗完成次数及放疗剂量达40Gy时生活质量评分情况。结果:营养干预组的放疗中断率为2.3%(1/43),对照组为18.6%(8/43),P=0.03;营养干预组完成化疗周期数为4.0±0.98,对照组为3.3±1.28,P=0.005;放射剂量达40Gy时两组患者QOL评分的差异有统计学意义(P<0.01)。结论:营养干预能有效提高宫颈癌患者同步放化疗的耐受性,提高其生活质量。Objective：To investigate the effect of nutritional intervention on tolerance and quality of life in cervical cancer patients receiving concurrent chemoradiotherapy.Methods：All 86 cervical cancer patients receiving concurrent chemoradiotherapy were randomly divided into the nutritional intervention group （n =43）and the control group （n =43）.To observe the radiotherapy interruption rates and the completed chemotherapy cycles.The quality of life when patients received radiotherapy dosages to 40Gy were detected by EORTC QLQ -C30.Results：The radiotherapy inter-ruption rates of the nutritional intervention group and the control group were 2.3%（1 /43）and 18.6%（8 /43）,P =0.03.The completed chemotherapy cycles of the nutritional intervention group and the control group were 4.0 ±0.98 and 3.3 ±1.28,P =0.005.The quality of life when patients received radiotherapy dosages to 40Gy had significantly different scores between the two groups （P 〈0.05）.Conclusion：Nutritional intervention can effectively improve the tolerance and quality of life in cervical cancer patients receiving concurrent chemoradiotherapy.

关 键 词：宫颈癌 营养干预 生活质量 放疗 化疗 

分 类 号：R737.33[医药卫生—肿瘤]