以类白血病反应为突出表现的多发性骨髓瘤一例报道  

Multiple Myeloma With Leukemoid Reaction as the Main Manifestation: A Case Report

作　　者：谭芬[1] 周锐[1] 徐运孝[2] 王凯歌[1] 

机构地区：[1]中南大学湘雅二医院呼吸内科,湖南省长沙市410011 [2]中南大学湘雅二医院血液内科,湖南省长沙市410011

出　　处：《中国全科医学》2015年第24期2976-2978,共3页Chinese General Practice

摘　　要：多发性骨髓瘤(MM)是浆细胞恶性增殖性疾病,骨髓中克隆性浆细胞异常增生,并分泌单克隆免疫球蛋白或其片段(M蛋白),导致相关器官或组织损伤。MM作为一种恶性肿瘤,可通过刺激骨髓引发类白血病反应,类白血病反应本身不需要治疗,其临床意义在于不要误诊,在临床上需与白血病加以鉴别。本文报道了1例以类白血病反应为突出表现的MM患者的诊治过程。Multiple myeloma （ MM） is a plasmocyte malignant proliferative disease .It causes dysplasia of clonal plasmocyte in marrow, brings the secretion of monoclonal immune globulin or its fragment （M protein）, it induces ROTI.As a malignant tumor , and induces leukemoid reaction by stimulating marrow .There is no need to treat leukemoid reaction , thus it needs to be differentiated from leukemia in order to avoid misdiagnosis .The article made a report of the diagnosis and treatment of a MM patient with leukemoid reaction as the prominent manifestation .

关 键 词：多发性骨髓瘤 类白血病反应 病例报告 

分 类 号：R733.3[医药卫生—肿瘤]