^(18)F-FDG PET/CT评价脑出血方面的临床价值  

Prognostic value in patients with intracerebral hemorrhage by PET-CT

作　　者：林耀云[1] 张琳焓[1] 林琳[1] 韩巍[1] 王家富[1] 王丽范[1] 何锦[1] 李勇[1] 

机构地区：[1]哈尔滨医科大学附属第一医院PET-CT室,黑龙江哈尔滨150001

出　　处：《中国实验诊断学》2015年第8期1274-1276,共3页Chinese Journal of Laboratory Diagnosis

摘　　要：目的为了观察脑出血患者病灶及周围区域葡萄糖代谢变化的规律,评价18F-FDG PET/CT在脑出血方面的临床应用价值。方法本研究选择经过保守干预的8名基底节区脑出血患者。在干预前和干预后30天分别行头部18F-FDG PET/CT扫描,对比分析干预前后出血病灶、病灶周围缺血区葡萄糖代谢变化的情况。结果干预前后,脑出血病灶区域的像素亮度值分别为:659.8±233.6、957.6±185.0,P<0.05,具有统计学差异;干预前后病灶周围缺血区像素亮度值分别为:351.8±146.1、573.9±162.6,P<0.05,具有统计学差异。结论 1干预前后,脑出血病灶、病灶周围缺血区的葡萄代谢差异明显。18F-FDG PET/CT影像在反映病变糖代谢变化时具有优势。2脑出血病灶周围缺血区域的葡萄代谢值在干预后均得到了不同程度的恢复,但恢复程度与干预后患者恢复程度的相关性并不明确。Objective To analyze glucose metabolism in cerebral hemorrhage,ischemia and prognosis the value in patients wcth iottracerebral hemorrhage by PET/CT.Methods to study 8 patients with basal ganglia hemorrhage who are received twice head 18 F-FDG-PET/CT scan within 30 days.Compare the datum before treatment with after treat-ment.Results We got twice data from pre and post treatment respectively.The pixel brightness values of cerebral hem-orrhage：659.8±233.6、957.6±185.0,P 〈0.05;The pixel brightness values around ischemia：351.8±146.1,573.9± 162.6,P 〈0.05）.Conclusion ①The glucose metabolism in cerebral hemorrhage and ischemia lesion is no significant difference before and after treatment.18 F-FDG-PET/CT scan has the advantage.②The glucose metabolism in ischemic area had different degree recovery,but they are no exactly relation between the recovery and after treatment were different degree of recovery,but the degree of glucose metabolism recovery and patients’.

关 键 词：脑出血 18F-FDG PET-CT 

分 类 号：R743.34[医药卫生—神经病学与精神病学] R817.4[医药卫生—临床医学]