安徽省阜阳市妇科门诊2140例宫颈乳头瘤病毒感染流行病学分析  

The epidemiological analysis of 2 140 cervical human papilloma virus infection cases in Fuyang Anhui

作　　者：王琳慧[1] 刘筱英[1] 丁家柱 邢文海 

机构地区：[1]安徽省阜阳市第五人民医院妇产科,236000 [2]安徽省阜阳市第五人民医院病理科,236000

出　　处：《蚌埠医学院学报》2015年第7期915-917,共3页Journal of Bengbu Medical College

摘　　要：目的:调查安徽省阜阳地区门诊患者人乳头瘤病毒(HPV)感染情况,分析该地区宫颈HPV 23种基因亚型感染及分布情况。方法:对2 140例接受妇科HPV检测的患者进行病理诊断,采用基因芯片技术导流杂交方法进行HPV亚型分型检测。结果:HPV总感染率为28.8%,单一感染占58.3%,高危型HPV感染率为22.9%。最常见的HPV感染为HPV16(21.4%)、HPV58(9.5%)、HPV52(7.3%)、HPV31(6.0%)、HPV18(5.8%);高危型HPV感染率和HPV各亚型感染率在各年龄组分布差异无统计学意义(P>0.05)。结论:该地区妇女宫颈HPV感染以HPV16、52、58型为主,基因亚型分布具有区域特异性。Objective：To investigate the human papilloma virus （HPV） infection, and analyze the infection and distribution of 23 HPV subtypes in Fuyang area. Methods：The pathological diagnosis in 2 140 HPV detection women were implemented,the HPV subtype was analyzed using the flow-through hybridization and gene-chip. Results：The total infection, single infection and high-risk infection rates of HPV were 28.8% ,58.3% and 22.9% ,respectively. The most common types of HPV infections were in turn HPV16（21.4% ）, HPV 58（9.5% ） ,HPV 52（7.3% ） ,HPV 31 （6.0%） and HPV 18（5.8% ）. The difference of the infection rates between high-risk type and each HPV subtype was not statistically significant（ P 〉 0.05 ）. Conclusions： HPV16,52 and 58 types are the main infection type of HPV. the distribution of HPV subtvne has regional soecificitv in Fuvan~ area.

关 键 词：人乳头瘤病毒 基因分型 流行病学 

分 类 号：R737.33[医药卫生—肿瘤]