成人肺母细胞瘤临床病理观察  

Adult type pulmonary blastoma: a clinicopathological study

作　　者：崔红霞[1] 郭玲玲[1] 冯一中[1] 张永胜[1] 

机构地区：[1]苏州大学附属第二医院病理科,江苏苏州215004

出　　处：《诊断病理学杂志》2015年第8期482-484,共3页Chinese Journal of Diagnostic Pathology

摘　　要：目的观察肺母细胞瘤的临床病理特点、诊断与鉴别诊断及预后。方法对1例手术切除的肺母细胞瘤进行临床特征、病理组织学特征以及免疫组化染色观察,并结合文献复习。结果肺母细胞瘤无明显的临床特征,组织学上由分化较好的恶性原始上皮细胞和较幼稚的恶性间叶成分构成,排列成大小不等的腺管样,散在分布于幼稚的间质背景上。无特异的免疫组化特征,易与其他疾病混淆。结论肺母细胞瘤是一种恶性度较高的恶性肿瘤,应与胸膜肺母细胞瘤、肺癌肉瘤、肺多形性癌鉴别;手术切除是最常用的治疗方法,受肿瘤的大小、组织成分等影响,预后差异较大。Objective To discuss and summarize the clinical pathological characteristics, diagnosis, differential diagnosis and prognosis of pulmonary blastoma. Methods The clinical features, pathological histology and immunohistochemical characteristics were observed in one case of pulmonary blastoma with review of the literature.Results Pulmonary blastoma had no obvious clinical features. Histologically,it consisted of precursor malignant epithelial cells with well-differentiation and immatured malignant mesenchymal elements; these cells arranged in glandular pattern of various size, and scattered in the immature mesenchymal background. There was no specific immunohistochemical characteristic of these structures and it was easy to be confused with other diseases. Conclusion Pulmonary blastoma is a high malignant tumor. It should be differentiated from pleuropulmonary blastoma, pulmonary carcinosarcoma and pulmonary pleomorphic carcinoma. Surgical resection is the most commonly used treatment. The blastoma size and tissue compositions make a great difference in prognosis.

关 键 词：成人 肺母细胞瘤 胸膜肺母细胞瘤 病理特点 

分 类 号：R734.2[医药卫生—肿瘤]