肝细胞癌放射治疗研究进展  

The Progress of Radiotherapy of Hepatocellular Carcinoma

作　　者：梁永 何克菲[2] 

机构地区：[1]桂平市人民医院肿瘤科,广西桂平537200 [2]南方医科大学珠江医院肿瘤科,广州510282

出　　处：《医学综述》2015年第16期2929-2932,共4页Medical Recapitulate

摘　　要：近几年,不同的外照射放射治疗技术以及联合其他治疗方法在肝细胞癌治疗中取得了较大进展。单纯放射治疗对早期患者可治愈,对中、晚期患者可延长生命,并可减轻疼痛。放射治疗与经导管动脉化疗栓塞术或口服索拉非尼或静脉化疗等方法联用,疗效可进一步提高,且毒性可耐受。因目前文献均局限于Ⅰ期/Ⅱ期临床试验或回顾性分析,故放射治疗在肝细胞癌综合治疗中的潜在作用,还需要开展Ⅲ期研究来证实。The external beam radiotherapy alone or combining with other therapy in hepatocellular carcinoma have made greater progress in recent years. It not only can cure hepatocellular carcinoma in early stage,but also can prolong life and reduce pains of patients in advance stage. Radiotherapy may improve the efficiency for advance patients,if combining with transcatheter arterial chemoembolization,sorafenib or chemotherapy,while the toxicity is still tolerable. Since the current literature is from phaseⅠ / Ⅱ clinical study or retrospective analysis,the potential role of radiotherapy in the comprehensive treatment of hepatocellular carcinoma still needs phase Ⅲ study.

关 键 词：肝细胞癌 放射疗法 经导管动脉化疗栓塞 索拉非尼 化学疗法 

分 类 号：R730.55[医药卫生—肿瘤]