18F-FDG符合线路SPECT显像与螺旋CT在乳腺癌术后转移中的诊断价值比较  

The comparison of the diagnostic values of 18F-FDG-SPECT and helical CT in the detection of the metastasis of postoperative breast cancer

作　　者：何健[1] 李素平[2] 唐恭顺[3] 

机构地区：[1]成都市第二人民医院核医学科,成都610017 [2]川北医学院附属医院核医学 [3]四川大学华西医院核医学科

出　　处：《中国医师杂志》2015年第8期1164-1166,1169,共4页Journal of Chinese Physician

基　　金：国家自然科学基金资助项目（30970859）

摘　　要：目的 比较18F-脱氧葡萄糖（18F-FDG）符合线路单光子发射计算机断层成像（SPECT）显像与螺旋CT在乳腺癌术后转移中的诊断价值.方法 选择乳腺癌术后患者94例为研究对象,术后均随访2年,随访期间均接受1s F-FDG符合线路SPECT显像与螺旋CT检查,并对怀疑术后转移的淋巴结进行活组织病理学检查.比较两种影像学检查对乳腺癌术后转移的诊断价值.结果 18F-FDG-SPECT检查的灵敏度、特异度、阳性预测值、阴性预测值以及阳性似然比高于螺旋CT检查,而阴性似然比低于螺旋CT检查,差异均有统计学意义（P＜0.05）.结论 18F-FDG符合线路SPECT显像比螺旋CT能更加有效诊断乳腺癌的术后转移.Objective To compare the diagnostic values of 18F-fluorodeoxyglucose-single photon emission computed tomography （18F-FDG-SPECT） and helical CT in the detection of the metastasis of postoperative breast cancer.Methods A total of 94 patients with postoperative breast cancer were chosen as research objects.The follow-up duration of post-operation was 2 years.All patients were received by 18F-FDG-SPECT and helical CT during follow-up.Lymph nodes that were suspected to the postoperative metastasis were taken for histological procedure.The diagnostic values of 18F-FDG-SPECT and helical CT to the metastasis of postoperative breast cancer were compared.Results Compared to helical CT,the sensitivity,specificity,positive predictive value,negative predictive value,and positive likelihood ratio of 18F-FDG-SPECT were higher （P ＜ 0.05）;however,the negative likelihood ratio of 1s F-FDG-SPECT were lower （P ＜ 0.05）.Conclusions 18F-FDG-SPECT has more important clinical value in the detection of metastasis of postoperative breast cancer relative to helical CT.

关 键 词：氟脱氧葡萄糖F18 体层摄影术 发射型计算机 单光子 体层摄影术 螺旋计算机 乳腺肿瘤/放射摄影术 肿瘤转移/放射摄影术 

分 类 号：R737.9[医药卫生—肿瘤] R730.44[医药卫生—临床医学]