青少年特发性脊柱侧凸患者的骨强度特征研究  

Study of bone strength in patients with adolescent idiopathic scoliosis

作　　者：周璇[1] 杜青[1] 陈佩杰[2] 励建安[3] 赵黎[4] 陈楠[1] 张树新[1] 梁菊萍[2] 

机构地区：[1]上海交通大学医学院附属新华医院康复医学科,上海200092 [2]上海体育学院运动科学学院 [3]江苏省人民医院康复医学科 [4]上海交通大学医学院附属新华医院儿童骨科

出　　处：《中华物理医学与康复杂志》2015年第8期589-592,共4页Chinese Journal of Physical Medicine and Rehabilitation

基　　金：上海市科学技术委员会资助项目（13401903400）;崇明县科学技术委员会资助项目（CKY2013-03）;新华人才基金项目（12XJ22001）;上海市残联系统康复人才优秀学科带头人培养计划

摘　　要：目的探讨青少年特发性脊柱侧凸（AIS）患者的骨强度特征。方法选取68例AIS患者作为AIS组，20例健康青少年作为正常对照组，采用超声骨强度仪测定研究对象桡骨远端的声速（SOS）、Z值、百分位。结果AIS组SOS、Z值、百分位均低于正常对照组，差异有统计学意义（P〈0．05）。不同类型、不同性别AIS患者的SOS、Z值、百分位之间比较，差异无统计学意义（P〉0．05）。AIS患者的年龄与SOS呈正相关，其最大Cobb角与SOS之间无明显相关性。结论AIS患者存在骨质强度偏低现象，其骨质强度与年龄呈正相关，与侧凸类型、性别之间无明显相关性。Objective To investigate the bone strength of adolescent idiopathic scoliosis （AIS） patients. Methods A total of 68 AIS patients and 20 healthy subjects were recruited. Speed of sound （ SOS）, Z-score and percentile of distal radius of normal subjects and AIS patients were measured using the quantitative ultrasound. Results Compared with normal controls, AIS had significantly lower average SOS, Z value and percentile. No sig- nificant difference was found among different curve patterns and gender of AIS patients. There was a positive correlation between SOS and age in AIS patients. However, there was no correlation between SOS and maximal Cobb angle in AIS patients. Conclusions AIS patients have lower bone strength generally. The bone strength has a positive correlation with the age, but no correlation with the curve pattern and gender in AIS patients.

关 键 词：青少年 特发性 脊柱侧凸 骨强度 

分 类 号：R682.3[医药卫生—骨科学]