外科手术治疗老年喉癌效果的影响因素分析  

INFLUENCE FACTORS OF SURGICAL OPERATION EFFECT IN TREATMENT OF ELDERLY PATIENTS WITH LARYNGEAL CANCER

作　　者：黄家军[1] 周小柳[1] 李智群[1] 潘雅[1] 曾银萍 

机构地区：[1]海南医学院附属医院耳鼻喉科,海南省海口市570102

出　　处：《中国煤炭工业医学杂志》2015年第9期1518-1521,共4页Chinese Journal of Coal Industry Medicine

基　　金：2012年度山东省优秀中青年科学家科研奖励基金项目(编号:2012BSE27043)

摘　　要：目的探讨临床外科手术治疗老年喉癌效果的影响因素。方法回顾性分析该院2008年2月—2010年2月收治的84例老年喉癌患者的临床资料,均实施手术治疗。术后随访5年,了解患者的5年生存情况,并对相关影响因素进行分析。结果经随访有7例患者因联系方式变更失访,随访率为91.67%(77/84)。随访5年,有27例患者死亡,50例患者存活,生存率为59.52%(50/84)。经单因素分析,显著影响患者5年生存情况的因素包括年龄、病理分级、肿瘤大小、原发部位,以及治疗方式和淋巴结转移、TNM分期,均P<0.05。经多因素Cox回归分析,可得原发部位和治疗方式以及淋巴结转移和TNM分期是影响外科手术治疗老年喉癌效果的独立因素,均P<0.05。结论影响外科手术治疗老年喉癌效果的因素包括原发部位和治疗方式以及淋巴结转移和TNM分期。Objective To explore the influence factors of surgical effect in treatment of elderly patients with laryngeal cancer. Methods A retrospective analysis was performed on the clinical data of 84 cases of senile patients with laryngeal carcinoma in author＇s hospital from February 2008 to February 2010, and were given operation treatment. Patients were followed up for 5 years, understanding the patient＇s 5 year survival situ- ation, and analyzed the correlative factors. Results After the follow- up of 7 patients for the change of contact was lost to follow- up, follow- up rate was 91.67% （77/84）. During 5 years of follow- up, 27 patients died, 50 cases survived, the survival rate was 59.52% （50/84）. By single factor analysis, inclu- ding age, histological grade, tumor size, site of the primary factors of 5 year survival were significantly af- fected patients, treatment method, lymph node metastasis and TNM stage; Multivariate Cox regression a- nalysis showed that the primary site, treatment method, the lymph node metastasis and TNM stage were independent factors affecting the effect of surgical treatment of aged patients with laryngeal carcinoma, all P〈0.05. Conclusion Influence factors of surgical operation effect in treatment of elderly patients with la- ryngeal cancer include the primary site, treatment method, the lymph node metastasis and TNM stage.

关 键 词：喉癌 外科手术 影响因素 老年人 

分 类 号：R739.6[医药卫生—肿瘤]