天津市大肠癌筛查初步结果分析  

Analysis of colorectal cancer screening practices in the general population of Tianjin

作　　者：赵丽中[1] 张伟华[1] 马东旺[1] 李文[1] 曹雅静[1] 王宏磊[1] 许晨[1] 石松荔[1] 黑君晖 王西墨[2] 

机构地区：[1]天津市人民医院大肠癌筛查项目办公室,天津市300121 [2]天津市大肠肛门病研究所

出　　处：《中国肿瘤临床》2015年第15期760-764,共5页Chinese Journal of Clinical Oncology

摘　　要：目的：在40～74岁天津市自然人群中开展大肠癌筛查，评价问卷调查、大便潜血检查（stool occult blood test，FOB）和全结肠镜检查的筛查效果，为探索大肠癌筛查策略提供参考。方法：筛查方法采用问卷调查结合FOB的两步筛查模式，经初筛确定的高危人群行全结肠镜检查明确诊断。结果：2012年5月至2014年12月，实际完成初筛2117304例，初筛顺应性39.72%；检出高危人群126118例，高危人群比例5.96%；全结肠镜检查25837例，检出腺瘤8095例，进展期腺瘤1236例、伴中重度异型增生的其他病变134例、早期癌112例、晚期癌336例，早诊率为81.52%。结论：天津市大肠癌筛查方案可以显著浓缩大肠癌高危人群，提高全结肠镜检查的阳性率，节省医疗资源。Objective：Colorectal cancer screening was performed on a general population with age ranging between 40 and 74 years old to evaluate the screening effects of questionnaire survey, fecal occult blood （FOB） test, and colonoscopy, as well as to provide some implications of colorectal cancer screening strategies. Methods： Two-step screening model of questionnaire survey combined with FOB test was applied for the screening. Colonoscopy was conducted in a high-risk population identified through preliminary screening as final diagnosis. Results：Based on the 2,117,304 cases screened, the screening compliance was 39.72%, and 126,118 cases （5.96%） were identified as high risk. Colonoscopies were performed on 25,837 cases, of which 8,095, 1,236, 134, 112, and 336 were identified as adenoma, advanced adenoma, severe dysplasia lesions, early cancer, and advanced cancer, respectively. The early stage di-agnostic rate was 81.52%. Conclusion：The colorectal cancer screening method performed in Tianjin can significantly concentrate on the high-risk population with colorectal cancer, increase the positivity rate of total colonoscopy, and economize medical resources.

关 键 词：大肠癌 大便潜血检查 全结肠镜检查 筛查 早诊早治 天津市 

分 类 号：R735.34[医药卫生—肿瘤]