骨髓间充质干细胞应用于角膜疾病的研究进展  

Progress of bone marrow mesenchymal stem cells for treatment of corneal diseases

作　　者：靳娜[1] 刘红玲[1] 张春梅[1] 傅少颖[1] 

机构地区：[1]哈尔滨医科大学附属第一医院眼科,中国黑龙江省哈尔滨市150001

出　　处：《国际眼科杂志》2015年第9期1546-1549,共4页International Eye Science

基　　金：国家自然科学基金资助项目(No.81301325)~~

摘　　要：随着干细胞科学的飞速发展,近年间充质干细胞(MSCs)的研究已成为热点。骨髓间充质干细胞(BMSCs)是来源于骨髓中的MSCs,具有免疫原性低、有多向分化潜能、促进损伤修复、性能稳定等生物学优点。研究发现,BMSCs是医学领域中极具前景的一种特殊细胞,几乎在各系统疾病的治疗方面都有广泛应用。眼科学者的研究也发现,BMSCs已经成为角膜疾病中一种兼具科研价值和临床价值的种子细胞,为角膜盲患者的康复带来了一线希望。本文就BMSCs对角膜损伤与角膜移植排斥反应治疗方面的研究做一综述。In recent years, with the rapid development of stem cells science, mesenchymal stem cells （MSCs） have become a research hotspot. Bone marrow mesenchymal stem cells （BMSCs） are MSCs that derived from bone marrow with some advantages, such as the potential of multi- directional differentiation, low immunogenicity, promoting damage repair and stable performance. The study by many scholars found that BMSCs are promising special cells in the field of medicine, and BMSCs have been widely used in almost every system in treatment of disease. For treatment of corneal disease, ophthalmology scholars found that BMSCs have already become a kind of seed cells with clinical and science value. BMSCs brought promising to the patients who have complex corneal disease. In this paper, we introduce the function of BMSCs on the treatment of corneal injury and corneal allograft rejection.

关 键 词：骨髓间充质干细胞 角膜损伤 角膜移植排斥反应 

分 类 号：R772.2[医药卫生—眼科]