中国老年人群阿尔茨海默病相关危险因素分析  

Analysis of Risk Factors of Alzheimer's Disease in Chinese Elderly Population

作　　者：刘晓秋[1] 白志军[2] 

机构地区：[1]南方医科大学公共卫生学院心理学系,广东广州510515 [2]广州市疾病预防控制中心,广东广州510440

出　　处：《医学与哲学（B）》2015年第7期43-46,共4页Medicine & Philosophy(B)

摘　　要：采用Meta分析方法综合筛选中国老年人群阿尔茨海默病的主要危险因素。共纳入17篇文献。病例组共计2 422例阿尔茨海默病患者,对照组共计3 940例。Meta分析结果提示,在纳入分析的9个危险因素中,与阿尔茨海默病发病关联较高的因素是具有糖尿病病史、负性生活事件多、受教育程度低以及年龄大于70周岁的老年人群。因此,患有基础疾病(糖尿病和高血压)、生活中负性生活事件多、教育程度低以及年龄高等因素会增加阿尔茨海默病的发病风险。To assess risk factors associated with Alzheimer＇s disease by the method of Meta-analysis. A total of 17 case-control studies were included, including 2 422 cases and 3 940 controls. The results of Meta-analysis suggested that, the first four risk factors related to postpartum depression were diabetes mellitus, negative life events, low education level, and age〉70 years old. Therefore, many risk factors may increase the incidence of Alzheimer＇s disease, like underlying health problems （hypertension and diabetes mellitus）, negative life events, unhealthy life patterns （alcohol drinking, insufficient sports activities and insufficient social amusements）, low education level and advanced age.

关 键 词：阿尔茨海默病 危险因素 META分析 病例-对照研究 

分 类 号：R741.02[医药卫生—神经病学与精神病学]