溃疡性结肠炎患者血清PLT、ESR、CRP的临床意义及红藤肠安汤的干预作用  

Significance of platelet count,erythrocyte sedimentation rate and C-reactive protein levels in patients with ulcerative colitis and intervention function of Hongteng chang'an decoction

作　　者：孙吉[1] 王宏伟[1] 孔婧[1] 周斌贝 汤瑾[1] 

机构地区：[1]上海中医药大学附属岳阳中西医结合医院消化科,上海200437

出　　处：《实用临床医药杂志》2015年第15期52-54,共3页Journal of Clinical Medicine in Practice

基　　金：上海申康医院发展中心中医药验方项目(SHDC12012048)

摘　　要：目的探讨溃疡性结肠炎(UC)患者血小板计数(PLT)、血沉(ESR)和外周血C反应蛋白(CRP)水平的临床意义及红藤肠安汤的干预作用。方法收集活动期UC患者74例及健康对照者30例。比较PLT、ESR和CRP在不同严重程度UC患者中的差异,分析其与疾病严重程度的相关性。结果不同严重程度UC患者血清PLT、ESR和CRP水平存在显著差异,且均高于健康者(P<0.05),其水平与疾病程度呈正相关(r=0.39,P<0.05)。红藤肠安汤治疗后,患者血清PLT、ESR和CRP水平较治疗前明显下降(P<0.05)。结论 PLT、ESR和CRP水平可以反映UC患者的临床严重程度,而红藤肠安汤能降低UC患者PLT、ESR和CRP水平。Objective To explore the significance of platelet count （PLT）, erythrocyte sedi- mentationrate （ESR） and C- reactive protein （CRP） levels in patients with ulcerative colitis （UC） and intervention function of Hongteng chang＇an decoction. Methods Seventy patients with active UC and thirty healthy people were collected. The differences of PLT, ESR and CRP levels in patients with different degree of UC were compared, and the correlation between levels and se- vere degree of disease were analyzed. Results There were significant differences of PLT, ESR and CRP levels in patients with different degree of UC, which were also significantly higher than those of the healthy people （P 〈 0.05）, and the levels of these indexes were correlated with extent of the disease （ r = 0.37, P 〈 0.05）. After treatment of Hongteng chang＇ an decoction, serum PLT, ESR and CRP levels decreased significantly in patients with active UC when compared with the levels before treatment （P 〈 0.05）. Conclusion Levels of PLT, ESR and CRP can reflect the severe degree of active UC patients, and the Hongteng chang＇ an decoction can reduce the PLT, ESR and CRP levels.

关 键 词：溃疡性结肠炎 血小板计数 血沉 C反应蛋白 

分 类 号：R574.62[医药卫生—消化系统]