695名0～12岁儿童维生素D及骨营养状况分析研究  

Analysis for the research of vitamin D and bone nutritional condition of 695 children,aged 0-12

作　　者：阎亚琼[1] 刘晓莉[1] 白增华[1] 穆文娟[1] 

机构地区：[1]山西省儿童医院妇幼保健院,太原030013

出　　处：《中国优生与遗传杂志》2015年第8期123-124,114,共3页Chinese Journal of Birth Health & Heredity

摘　　要：目的了解0~12岁儿童维生素D及骨营养的状况,并探讨维生素D的含量对儿童骨营养的影响。方法儿童保健门诊2013年1月-2014年1月来我院儿保门诊健康体检695名0~12岁儿童,采用酶联免疫法进行血清25-（OH）D检测,采用定量超声技术（QUS）测定超声速度值（SOS）,根据同年龄、同性别SOS标准值的百分位数划成低骨强度和正常骨强度。结果 25-（OH）D的平均浓度为（64.15±31.69nmol/L）,男性与女性25-（OH）D水平差异无统计学意义（t=1.631,P〉0.05）;维生素D缺乏组的低骨密度发生率大于维生素D正常组,前者骨的SOS值小于后者,两者统计学具有显著差异（P〈0.05）。结论维生素D缺乏会影响儿童骨营养的状况乃至骨的发育,应重视3~12岁儿童维生素D的补充,增强少年儿童的身体素质。Objective：To understand children at age from 0~12 about the condition of vitamin D and osteotrophy,also having a discussion about the influence of content of vitamin D to children. Methods：From January 2013 to January 2014,well baby clinic have 695 children aged 0~12 did the physical examination,detect the ELISA serum 25-（OH）D by using quantitative ultrasound（QUS）measurement of ultrasonic velocity values（SOS）,according to the same age,same gender SOS standard value percentile has been classified into low bone strength and normal bone strength. Results：The mean concentration of 25-（OH）D was（64.15 ± 31.69nmol/L）,male and female 25-（OH）D levels had no significant difference（t = 1.631,P〉0.05）;for vitamin D deficient group,the incidence of low bone density is greater than normal vitamin D,and for the bone SOS values,it is smaller than the latter,both statistically significant differences（P〈0.05）. Conclusion：Vitamin D deficiency can affect bone nutrition status of children and even bone development,we should pay attention to children aged 3 to 12 to supplement vitamin D,and enhance children′s physical fitness.

关 键 词：维生素D 儿童 骨强度 骨营养 

分 类 号：R153.2[医药卫生—营养与食品卫生学]