支架置入技术治疗食道癌的临床疗效及预后  

Curative Effect and Prognosis of Esophageal Stent Implantation in Esophageal Cancer

作　　者：洪慧玲[1] 王煜[1] 郑亦农[1] 郑可造[1] 陈雍[1] 

机构地区：[1]皖南医学院附属黄山市人民医院,安徽黄山245000

出　　处：《现代生物医学进展》2015年第19期3674-3677,共4页Progress in Modern Biomedicine

基　　金：教育部高等学校博士学科点专项科研基金项目(20110001110054)

摘　　要：目的:观察支架置入法对食道癌患者的治疗效果及预后情况。方法:选取我院收治的食道癌患者共104例,根据治疗手段分为两组,其中对照组52例采用70 Gγ7/周治疗方案;实验组52例给予支架置入法治疗。对两组患者的梗阻改善情况、生存质量评分、并发症及生存情况进行统计分析。结果:1治疗后,两组患者的梗阻情况以及生存质量均得到有效改善,实验组患者的梗阻总缓解率为92.31%,生存质量评分为42.61±5.23分,均显著高于对照组,差异具有显著性(P<0.05);2实验组患者的不良反应发生率(36.54%)与对照组(38.48%)比较无统计学差异(P>0.05);3两组患者的3个月及6个月时的生存率相接近,但是实验组患者12个月生存率(71.7%)显著低于对照组(82.7%),差异具有统计学意义(P<0.05)。结论:支架置入法能够显著改善食道癌患者的梗阻症状,提高患者生存质量,是较为安全可靠的缓解食道狭窄方法。Objective： To investigate the curative effects and prognosis of the esophageal stent implantation in the treatment of esophageal cancer. Methods： 104cases of esophageal cancer from our hospital were selected, and according to treatment methods they were divided into two groups, 52 cases each group. The patients in control group were used 70 G gamma 7/week treatment scheme; and the patients in the experimental group were given the implantation of stent, namely the placement of Ni Ti shape memory alloy coated stent. The improvement of obstruction, the score of quality of life, the complications and survival of all the patients were recorded and statistically analyzed. Results： （L）After treatment, the esophageal obstruction and life quality was effectively improved in these two groups. The total efficient rate of improvement of obstruction in the experimental group was 92.31%, and the quality of life score was 42.61＋ 5.23 points, which were significantly higher than that of control group, with significant difference （P〈0.05）;（~） The incidence of adverse reaction in experimental group （36.54% patients） and control group（38.48%） had no statistical difference（P〉0.05）; （~）Survival in 3 months and 6 months of two groups of patients were similar, but the patients in the experimental group and 12 months survival rate （71.7%） was significantly lower than the control group （82.7%）, with significant difference （P〈0.05）.Conclusions： The esophageal stent implantation can significantly improve the obstruction symptoms of patients with esophageal cancer, improve the survival quality, with more safety and higher efficiency to reduce esophageal stricture.

关 键 词：支架置入 食道癌 放疗 

分 类 号：R735.1[医药卫生—肿瘤]