非痴呆型血管性认知功能障碍的研究进展  

Research Progress of Vascular Cognitive Impairment No Dementia

作　　者：祝铁军[1] 刘彬[1] 于美婷[1] 齐慧萍[1] 王鹏军[1] 

机构地区：[1]哈尔滨医科大学附属第四医院神经内科,黑龙江哈尔滨150001

出　　处：《现代生物医学进展》2015年第20期3990-3992,4000,共4页Progress in Modern Biomedicine

基　　金：黑龙江省自然基金项目(D201167)

摘　　要：随着血管性痴呆(vascular dementia,VD)的发病率逐年升高,我们对血管性痴呆的研究也不断深入。目前国内外学者主张根据疾病的发展阶段对VD进行划分,从而针对不同阶段病情的发展进行有效的治疗,以免延误最佳治疗时机。非痴呆型血管性认知功能障碍(vascular cognitive impairment no dementia,VCIND)是血管性痴呆的早期阶段,多发生在血管性认知损害之前或早期。在认知损害发生之前,血管性因素及脑血管疾病是唯一可去除的病因,并且能够成为延缓甚至逆转痴呆进展的干预靶点。因此,早期诊断并及时治疗血管性因素及脑血管疾病对于降低血管性痴呆的发病率,预防血管性认知障碍(vascular cognitive impairment,VCI)具有重要意义。本文对近年来VCIND的流行病学、神经心理学、影像学、预防和治疗的进展作一综述。With the increasing morbidity and detailed recognition of vascular dementia （VD）, the researches have been more and more penetrating. At the present, the scholars mainly assert that the VD should be divided according to different developing stages of the disease so as to conduct the treatment in time. The vascular cognitive impairment no dementia （VC1ND） is the early stage of VD. Before the occurrence of congnitive obstacle, the vascular factors and cerebrovascular disease may be the essential pathogenesis which maight become the targeting to postpone or changover dementia. Therefore, it is beneficial to prevent and treat vascular cognitive impairment （VCI） by diagnosing VCIND earlier to wipe off the pathogenesis of vascular factor and cerebrovascular disease. This paper mainly reviews the epidemiology, the neuropsychology, the iconography, the prevention and the treatment of VCUND in recent years.

关 键 词：非痴呆型血管性认知功能障碍 脑血管病 神经心理学 影像学 治疗 

分 类 号：R749.13[医药卫生—神经病学与精神病学]