米油对急性腹泻患儿大便分泌型免疫球蛋白A含量及疾病转归的影响  

Effect of rice oil on secretory immunoglobulin A content in feces and disease outcome in children with acute diarrhea

作　　者：林莹[1] 杨军红[1] 陈颖新[1] 李萍[1] 安冬[1] 赵文卓[1] 田曦[1] 

机构地区：[1]天津市儿童医院营养科,300074

出　　处：《中华临床营养杂志》2015年第4期214-218,共5页Chinese Journal of Clinical Nutrition

基　　金：天津市卫生局科技基金（2013KZ039）

摘　　要：目的研究米油对急性腹泻患儿大便中分泌型免疫球蛋白A（sIgA）含量及疾病转归的影响。方法选取2013年1月至2014年10月天津市儿童医院住院的急性腹泻患儿180例。采用随机数码表法随机分为米油组、蒙脱石散组与对照组，每组60例。观察并比较3组患儿的疗效，腹泻、呕吐消退时间，住院时间及治疗前后大便sIgA含量。结果米油组及蒙脱石散组治疗总有效率（93．3％、96．7％）显著高于对照组（76．7％，P=0．011、0．001）；米油组及蒙脱石散组住院时间、腹泻消退时间、呕吐消退时间显著短于对照组[（5．6±1．4）、（5．7±1．6）d比（6．9±1．8）d；（3．7±0．9）、（3．5±0．9）d比（5．4±1．2）d；（2．8±0．6）、（3．2±0．8）d比（5．1±0．8）d；均P=0．000]；米油组治疗总有效率、住院时间、腹泻消退时间与蒙脱石散组比较差异无统计学意义（P=0．402、0．716、0．226），呕吐消退时间显著短于蒙脱石散组（P=0．016）。治疗前对照组、蒙脱石散组、米油组大便sIgA分别为0．527±0．133、0．487±0．109、0．534±0．150，3组间差异无统计学意义（P〉0．05）。治疗后第2天，米油组、蒙脱石散组大便中sIgA（0．669±0．176、0．612±0．161）显著高于对照组（0．541±0．149）（P=0．000、0．014），蒙脱石散组与米油组差异无统计学意义（P=0．067）；治疗后第4天，蒙脱石散组sIgA（1．981±0．462）显著高于对照组（1．762±0．378）（P=0．005），米油组sIgA（2．331±0．494）显著高于其他两组（P=0．000）。治疗后第2天与治疗前相比，对照组sIgA变化差异无统计学意义（P=0.295），蒙脱石散组及米油组sIgA均显著性升高（均P=0．000）；治疗后第4天与治疗后第2天相比，3组sIgA均显著性升高（均P=0．000）。结论米油治疗儿童急性腹泻疗效与蒙脱石散相同，对治疗呕吐及促进肠道sIObjective To study the effect of rice oil on secretory immunoglobulin A （sIgA） content in feces and disease outcome in children with acute diarrhea. Methods We selected 180 children with acute diarrhea hospitalized in Tianjin Children＇s Hospital during the period from January 2013 to October 2014. They were randomly divided with a random number table into rice oil group, montmorillonite powder group and control group （all n = 60）. The effect of treatment, duration before subsiding of diarrhea and vomit, length of hospital stay and sIgA content in feces before and after treatment were analyzed. Results The total effective rates in the rice oil group and the montmorillonite powder group （93. 3%, 96.7% ） were significantly higher than that in the control group （76. 7%, P =0. 011, P =0. 001 ）. Length of hospital stay, duration before subsiding of diarrhea and vomit in the rice oil group and the montmorillonite powder group were significantly shorter than those in the control group[ （5.6±1.4） d, （5.7±1.6） dvs. （6.9±1.8） d; （3.7±0.9） d, （3.5±0.9） dvs. （5.4± 1.2） d; （2.8±0.6） d, （3.2±0.8） d vs. （5.1±0.8） d; allP=0.000]. The total effeetive rates , lengthof hospital stay, duration before subsiding of diarrhea showed no statistically significant differences between the rice oil group and the montmorillonite powder group （P = 0. 402, 0. 716, 0. 226）, but the duration before subsiding of vomit in the rice oil group was significantly shorter than that in the montmorillonite powder group （P = 0. 016）. Before treatment, the slgA contents in feces in the control group, the montmorillonite powder group, the rice oil group were 0. 527 ± 0. 133, 0. 487 ± 0. 109, 0. 534± 0. 150, with no significant difference （ P 〉 0. 05 ）. Two days after treatment, slgA contents in the rice oil group and the montmorillonite powder group （0. 669 ±0. 176, 0. 612 ±0. 161 ） were significantly higher than in the control group （0. 541 ± 0. 149, P = 0. 000, 0. 014）

关 键 词：米油 急性腹泻 儿童 分泌型免疫球蛋白A 呕吐 

分 类 号：R725.7[医药卫生—儿科]