前列腺癌患者生存质量及影响因素分析  

Study on present situation of life quality and influence factors of patients with prostate cancer

作　　者：汪康宁[1] 廖秋玲[2] 陈烈钳 谭国斌[1] 张高华[3] 熊莽 柯龙志 张赛[1] 陈合格[1] 

机构地区：[1]广东医学院泌尿外科研究室,湛江524001 [2]广东医学院研究生学院 [3]广东医学院公共卫生学院

出　　处：《中国男科学杂志》2015年第6期15-20,共6页Chinese Journal of Andrology

基　　金：国家自然科学基金(81402118)

摘　　要：目的 探讨影响前列腺癌患者生存质量的相关因素.方法 采用世界卫生组织生存质量简表（WHOQOL-BREF）、家庭功能评估量表（APGAP）和抑郁自评量表（SDS）对我院泌尿外科住院的113名前列腺癌患者进行问卷调查.结果 全部113名前列腺癌患者生存质量得分生理、心理、社会关系和环境领域得分分别为（48.57±13.25）、（41.42±11.93）、（52.34±12.65）和（60.63±13.94）分;生理、心理、社会关系、环境领域生存质量得分高收入患者高于低收入患者（F=3.55、4.17、3.99、3.72,P＜0.05）,医保、新农合患者高于自费患者（F=5.44、3.94、6.04、6.22,P＜0.05）,无尿道压迫症状患者高于有尿道压迫症状患者（t =-2.22、-2.98、-2.03、-2.44,P＜0.05）;生理、心理和环境领域生存质量得分高文化程度患者高于低文化程度患者（F=3.16、3.67、8.68,P＜0.05）;生理、心理和社会关系领域生存质量得分病程短的患者高于病程长的患者（F=3.92、4.30、3.53,P＜0.05）,单纯手术患者高于其他治疗方式的患者（F=10.42、7.37、4.42,P＜0.05）;家庭功能障碍越严重,生存质量得分越低（F=6.66、4.02、3.79、1.68,P＜0.05）,抑郁状况越严重,生存质量得分越低（F=4.36、6.43、3.45、4.81,P＜0.05）;Logistic回归分析显示经济状况、尿道压迫症状、家庭功能和抑郁状况是前列腺癌患者生存质量自我综合评分的影响因素.结论 前列腺患者生存质量的影响因素主要有经济状况、付费方式、文化程度等.家庭功能、抑郁状况与前列腺癌患者生存质量明显相关.应充分利用家庭和社会的力量重视患者的身心健康,以提高前列腺患者的生存质量.Objective To explore and analyze the influence factors related to life quality of patients with prostate cancer. Methods A total of 113 patients with prostate cancer from urology department in our hospital were surveyed using the standard forms of World Health Organization quality of life-brief （WHOQOL-BREF）, family APGAR questionnaire and self-rating depression scale （SDS）,respectively. Results The scores in physiology, psychology, social relationship and environmental condition for 113 patients with prostate cancer were 48.57±13.25, 41.42±11.93, 52.34±12.65 and 60.63±13.94, respectively. The scores of high-income patients in physical, psychological, social relationships and environment conditions were significantly higher than those of the low-income patients （F=3.55, 4.17, 3.99, 3.72, P〈0.05）, and the scores of natients who have health insurance and new coonerative medical ,scheme（NCMS） were hit, her than those nfthe self-paid patients （F=5.44, 3.94, 6.04, 6.22, P〈0.05）, and the scores of patients without urethral pressure symptoms was higher than those of the patients with urethral pressure symptoms（t=--2.22, -2.98, -2.03, -2.44, P〈0.05）, the scores of patients with higher education level was higher than those of the lower ones（F=3.16, 3.67, 8.68, P〈0.05）, the score of patientes with shorter duration was higher than those of patients with longer duration（F=3.92, 4.30, 3.53, P〈0.05）, the score of patients treated with surgery alone was higher than those of patients treated by other methods （F=10.42, 7.37, 4.42, P〈0.05）. The more severe family dysfunction and the more severe depression, the lower life quality scores （F=6.66, 4.02, 3.79, 1.68, P〈0.05; F=4.36, 6.43, 3.45, 4.81, P〈0.05, respectively） was obtained in patients with prostate cancer. Logistic regression analysis showed that economic situations, urethral pressure symptoms, family roles and depression affected the self- evaluation scale of life quality in patients with prostate cancer. Conclusi

关 键 词：生活质量 抑郁 社会支持 前列腺肿瘤 

分 类 号：R737.25[医药卫生—肿瘤]