Synthesis and Evaluation of Sulfoxide-Functionalized BODIPYs as Chemosensors for Thiols  

作　　者：Chunchang Zhao Haifeng Jiang 

机构地区：[1]Key Laboratory for Advanced Materials and Institute of Fine Chemicals, East China University of Seience & Technology, Shanghai 200237, China

出　　处：《Chinese Journal of Chemistry》2015年第7期711-716,共6页中国化学（英文版）

基　　金：We gratefully acknowledge the financial support by the National Natural Science Foundation of China （Nos. 21172071, 21190033 and 21372083）.

摘　　要：BODIPY-based fluorescent chemosensors bearing sulfoxide function were designed and evaluated. Thiols triggered sulfoxide→sulfide transduction in these probes leads to an obvious red-shift in absorption and dramatic fluorescence enhancement with distinctly ratiometric features, enabling the accurate assay ofthiols in living cells.BODIPY-based fluorescent chemosensors bearing sulfoxide function were designed and evaluated. Thiols triggered sulfoxide→sulfide transduction in these probes leads to an obvious red-shift in absorption and dramatic fluorescence enhancement with distinctly ratiometric features, enabling the accurate assay ofthiols in living cells.

关 键 词：sulfoxide→sulfide transfer CYSTEINE RATIOMETRIC living cells reduction 

分 类 号：X824[环境科学与工程—环境工程] TP212.2[自动化与计算机技术—检测技术与自动化装置]