CYSTEINE

作品数：176被引量：474H指数：8
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Dietary supplementation with N‑acetyl‑L‑cysteine ameliorates hyperactivated ERK signaling in the endometrium that is linked to poor pregnancy outcomes following ovarian stimulation in pigs
《Journal of Animal Science and Biotechnology》2025年第1期167-181,共15页Linghua Cheng Zhicheng Shi Yuan Yue Yue Wang Yusheng Qin Wei Zhao Yupei Hu Qin Li Min Guo Lei An Shumin Wang Jianhui Tian 
National Natural Science Foundation of China(31930103);National Center of Technology Innovation for Pigs(NCTIP-XD/B03);Ningbo Major Science and Technology Project(2021Z112);National Key R&D Program(2022YFD1300303);Beijing Innovation Consortium of Livestock Research System BAIC05-2024.
Background Exogenous gonadotropin-controlled ovarian stimulation is the critical step in animal reproductive management,such as pig,sheep,bovine and other species.It helps synchronize ovulation or stimulate multiple o...
关键词：ESTRADIOL GONADOTROPIN Implantation N-ACETYL-L-CYSTEINE Ovarian stimulation Uterine receptivity 
Sulfur metabolism under stress:Oxidized glutathione inhibits methionine biosynthesis by destabilizing the enzyme cystathionineγ-synthase
《Journal of Integrative Plant Biology》2025年第1期87-100,共14页Yael Hacham Alex Kaplan Elad Cohen Maayan Gal Rachel Amir 
supported by the Israel Science Foundation(ISF Grant no.1857/20);Binational Agricultural Research&Development(BARD Grant no.IS-4248-09 R)。
Cysteine is the precursor for the biosynthesis of glutathione,a key stress-protective metabolite,and methionine,which is imperative for cell growth and protein synthesis.The exact mechanism that governs the routing of...
关键词：cystathionineγ-synthase(CGS) CYSTEINE GLUTATHIONE metabolic competition METHIONINE oxidative stress sulfur metabolism TOBACCO 
Investigating the expression profiles of cysteine string proteins(CSPs)in cochlear tissue
《Journal of Otology》2024年第4期193-199,共7页Shili Zhang Caiji Wang Yuehua Qiao Xi Shi 
supported by the Science and Technology Development aid Project of Xuzhou Science and Technology Bureau(KC21249);supported by Hainan Provincial Natural Science Foundation of China(824MS052);Scientific Research Startup Foundation of Hainan University.
Objective:This study aims to explore the expression patterns of cysteine string protein alpha(CSPα)and cysteine string protein beta(CSPβ)in the mammalian inner ear,with an emphasis on their temporal dynamics during ...
关键词：Cysteine string protein CSPα CSPβ Miniature pig C57BL/6 mouse 
MarR family proteins sense sulfane sulfur in bacteria
《mLife》2024年第2期231-239,共9页Guanhua Xuan Luying Xun Yongzhen Xia 
supported by the National Natural Science Foundation of China(Nos.92351302,91951202,and 32201982).
Members of the multiple antibiotic resistance regulator(MarR)protein family are ubiquitous in bacteria and play critical roles in regulating cellular metabolism and antibiotic resistance.MarR family proteins function ...
关键词：cysteine thiols disulfide bond MarR protein family ROS sulfane sulfur 
A near-infrared fluorescent probe for visualizing transformation pathway of Cys/Hcy and H2S and its applications in living system
《Chinese Chemical Letters》2024年第5期296-301,共6页Yudi Cheng Xiao Wang Jiao Chen Zihan Zhang Jiadong Ou Mengyao She Fulin Chen Jianli Li 
supported by the National Natural Science Foundation of China(Nos.22077099 and 22171223);the Innovation Capability Support Program of Shaanxi(Nos.2023-CX-TD-75 and 2022KJXX-32);the Technology Innovation Leading Program of Shaanxi(Program No.2023KXJ-209);the Natural Science Basic Research Program of Shaanxi(Nos.2022JQ-151 and 2023-JC-YB-141);Young Talent Fund of Association for Science and Technology in Shaanxi,China(No.SWYY202206);the Shaanxi Fundamental Science Research Project for Chemistry&Biology(Nos.22JHZ010 and 22JHQ080);the Yan’an City Science and Technology Project(No.2022SLZDCY-002).
Sulfydryl-contained(-SH)substances including hydrogen sulfide(H_(2)S),cysteine(Cys),homocysteine(Hcy)and glutathione(GSH)play crucial roles in living systems,and their variations are closely associated with various di...
关键词：Fluorescent probe NEAR-INFRARED Hydrogen sulfide Cysteine/homocysteine Large Stokes shift Dicyanoisophorone Drug-induced liver injury 
Adrenal pheochromocytoma impacts three main pathways: cysteine-methionine, pyrimidine, and tyrosine metabolism
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2024年第5期410-421,共12页Chong LAI Qingling YANG Yunuo ZHANG Renjie GONG Majie WANG Jiankang LI Maode LAI Qingrong SUN 
supported by the National Natural Science Foundation of China(No.82072811).
Pheochromocytomas and paragangliomas(PPGLs)cause symptoms by altering the circulation levels of catecholamines and peptide hormones.Currently,the diagnosis of PPGLs relies on diagnostic imaging and the detection of ca...
关键词：Pheochromocytoma and paraganglioma(PPGL) Metabolomics Gene set variation analysis L-Dihydroorotic acid Vanylglycol 
Fluorescent Probes for Cysteine and Cysteine Oxidation Imaging
《Chemical Research in Chinese Universities》2024年第2期225-236,共12页ZHANG Xia LI Guocheng PAN Wei LI Na LI Yanhua TANG Bo 
supported by the National Natural Science Foundation of China(Nos.22374092,22206117);the Project of Shandong Provincial Laboratory,China(No.SYS202207);the Youth Innovation Science and Technology Program of Higher Education Institution of Shandong Province,China(No.2021KJ030);the Fund of the Jinan Innovation Team,China(No.2021GXRC034);the Natural Science Foundation of Shandong Province,China(No.ZR2021QB147).
Cysteine is an important regulator of redox processes.Due to the nucleophilic and oxidative sensitivity,cysteine residues in proteins can be oxidized by intracellular reactive oxygen species(ROS),which can lead to pro...
关键词：CYSTEINE Cysteine oxidation Fluorescent probe Oxidative stress 
Metabolomic profiling reveals decreased serum cysteine levels during gestational diabetes mellitus progression
《Journal of Molecular Cell Biology》2024年第3期35-45,共11页Mengyu Lai Jiaomeng Li Jiaying Yang Qingli Zhang Yujia Gong Yuhang Ma Fang Fang Na Li Yingxiang Zhai Tingting Shen Yongde Peng Jia Liu Yufan Wang 
supported by grants from the National Natural Science Foundation of China(81870610);Shanghai Science and Technology Commission Foundation(21Y11904800 and 23ZR1451500);the Clinical Research Plan of SHDC(SHDC2020CR3065B);the National Key Research and Development Program of China(2021YFC2501600 and 2021YFC2501601).
Gestational diabetes mellitus(GDM)is a pregnancy-related metabolic disorder associated with short-term and long-term adverse health outcomes,but its pathogenesis has not been clearly elucidated.Investigations of the d...
关键词：gestational diabetes mellitus metabolomics CYSTEINE 
Photocaged activity-based probes for improved monitoring of protein S-sulfenylation in living cells
《Chinese Chemical Letters》2024年第2期451-454,共4页Jiahao Zhang Haiyue Peng Zi'an Chen Guorui Li Jing Huang 
supported by the National Natural Science Foundation of China(Nos.31871365 and 22177029);Fundamental Research Funds for the Central Universities.
Protein S-sulfenylation(protein sulfenic acid),as one of the most significant oxidative post-translational modifications(OxiPTMs),plays a vital role in regulating protein function.A variety of activity-based probes ha...
关键词：CYSTEINE Sulfenic acid Activity-based probe Photocage Light activation Protein S-sulfenylation 
Direct synthesis of unnatural amino acids and modifications of peptides via LADA strategy
《Chinese Chemical Letters》2024年第1期237-242,共6页Yunqi Liu Junliang Zhou Zhankui Sun 
Unnatural amino acids(UAAs)have broad applications in pharmaceutical sciences and biological studies.Current synthetic methods for UAAs mainly rely on asymmetric catalysis and often require several steps.There is a la...
关键词：Unnatural amino acids Peptide modifications DESULFURIZATION CYSTEINE Radical addition 
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