supported by grants from the National Natural Science Foundation of China(32425005 and 32121003);the National Key R&D Program of China(2021YFA1300702);supported by the National Natural Science Foundation of China(32072043,32072041,32072407 and 32401873);Natural Science Foundation of Sichuan Province(2023NSFSC0005,2024NSFJQ0007 and 2024NSFSC0322);the open fund of State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China(SKL-ZY202207);New Cornerstone Science Foundation through the XPLORER PRIZE and the New Cornerstone Investigator Program(Grant NCI202339)also supported this work.
Hydrogen peroxide(H2O2)is a ubiquitous signal regulating many biological processes,including innate immunity,in all eukaryotes.However,it remains largely unknown that how transcription factors directly sense H2O2 in e...
supported by the Israel Science Foundation(ISF Grant no.1857/20);Binational Agricultural Research&Development(BARD Grant no.IS-4248-09 R)。
Cysteine is the precursor for the biosynthesis of glutathione,a key stress-protective metabolite,and methionine,which is imperative for cell growth and protein synthesis.The exact mechanism that governs the routing of...
financially supported by National Natural Science Foundation of China(32072985,32273144);the earmarked fund for CARS(CARS-45);National Key R&D Program of China(2019YFD0900200)。
Background Methionine(Met)is the only sulfur-containing amino acid among animal essential amino acids,and methionine deficiency(MD)causes tissue damage and cell death in animals.The common modes of cell death include ...
funded by the National Key R&D Program of China(2021YFD1300404);the China Agriculture Research System program(CARS-40 and CARS-41);the Beijing Natural Science Foundation(NO.6222036);the Meat Chicken Science and Technology Backyard Program in Dongchengfang Town,Zhuozhou,Hebei Province,China(CAUZ2024013).
This study aimed to compare the effects of dietary methionine(Met)and 2-hydroxy-4-(methylthio)-butanoate(HMTBA)on the eggshell quality of broiler breeder hens and elucidate the mechanism of Met in improving eggshell q...
supported by grants from the National Key R&D Program of China(2023YFD2402000);the National Natural Science Foundation of China(32072986);the Agriculture Research System of Shanghai,China(202304);the China Agriculture Research System of MOF and MARA(CARS-48).
This study investigated the effects of dietary methionine(Met)on growth performance and protein synthesis in juvenile Chinese mitten crabs(Eriocheir sinensis)fed fish meal(FM)-free diets.Three diets free of FM contain...
financially supported in part by a cooperative agreement 6040–32000-080-000D from United States Department of Agriculture-Agricultural Research Service。
Background This study investigated effects of different methionine(Met)supplementation levels in a reduced protein diet on growth performance,intestinal health,and different physiological parameters in broilers under ...
supported by the 12th Five-Year Plan for Science and Technology Development of China(2012BAD33B05).
Methionine restriction(MR)is an effective dietary strategy to regulate energy metabolism and alleviate oxidative stress and inflammation in the body,especially in the middle-aged and elderly population.However,the hig...
National Natural Science Foundation of China(No.82173822).
Ulcerative colitis(UC)is associated with changed dietary habits and mainly linked with the gut microbiota dysbiosis,necroptosis of epithelial cells,and mucosal ulcerations.Liver dysfunction and abnormal level of liver...
supported by the program for Shanghai Rising Stars of Youth Medical Talents-Clinical Laboratory Practitioner Program of China(No.[2021]99).
Objective:Colorectal cancer(CRC),a common malignant tumor of the digestive tract,poses a worldwide threat to human health.Methods:This study conducted a narrative literature review to assess and provide perspectives o...
supported by the Basic and Applied Basic Research Foundation of Guangdong Province(2021A1515220185).
Non-alcoholic fatty liver disease(NAFLD)is a condition involving the accumulation of liver fat in excess of 5–10%of its weight after excluding excessive alcohol intake and any other causes of liver disease or steatos...