SERINE

作品数：133被引量：344H指数：9
导出分析报告
相关领域：医药卫生生物学更多>>
相关作者：王晶晶郭焱丁明孝陈建国蔡朝阳更多>>
相关机构：北京大学中国科学技术大学中国科学院上海生命科学研究院浙江大学更多>>
相关期刊：更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划中央高校基本科研业务费专项资金更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Bromodomain-containing protein 4 knockdown promotes neuronal ferroptosis in a mouse model of subarachnoid hemorrhage
《Neural Regeneration Research》2026年第2期715-729,共15页Peng Lu Fan Zhang Lei Yang Yijing He Xi Kong Kecheng Guo Yuke Xie Huangfan Xie Bingqing Xie Yong Jiang Jianhua Peng 
supported by the National Natural Science Foundation of China,Nos.82371310(to YJ),82271306(to JP);the Sichuan Science and Technology Support Program,Nos.2023YFH0069(to JP),2023NSFSC0028(to YJ),2023NSFSC1559(to YJ),2022YFS0615(to JP),2022NSFSC1421(to JP);Scientific Research Project of Sichuan Provincial Health Commission,No.23LCYJ040(to YJ);Youth Foundation of Southwestern Medical University and Southwest Medical University Project,Nos.2020ZRQNA038(to JP),2021ZKZD013(to JP),2021LZXNYD-P01(to YJ),2023QN014(to JP).
Neuronal cell death is a common outcome of multiple pathophysiological processes and a key factor in neurological dysfunction after subarachnoid hemorrhage.Neuronal ferroptosis in particular plays an important role in...
关键词：bromodomain-containing protein 4 cell death early brain injury ferritinophagy ferroptosis neurological deficits neuron oxidative stress RAF proto-oncogene serine/threonine-protein kinase(Raf-1) subarachnoid hemorrhage 
Supplementation of serine in low-gossypol cottonseed meal-based diet improved egg white gelling and rheological properties by regulating ovomucin synthesis and magnum physiological function in laying hens
《Journal of Integrative Agriculture》2025年第3期1152-1166,共15页Jianmin Zhou Yu Fu Uchechukwu Edna Obianwuna Jing Wang Haijun Zhang Xiubo Li Guanghai Qi Shugeng Wu 
financially supported by the National Natural Science Foundation of China(32072774);the China Postdoctoral Science Foundation(2023M733822);the Beijing Innovation Consortium of Agriculture Research System(BAIC04),China;the earmarked fund for CARS National System for Layer Production Technology,China(CARS-40);the Agricultural Science and Technology Innovation Program(ASTIP)of the Chinese Academy of Agricultural Sciences。
This study examined the effect of dietary serine(Ser)on egg white quality,ovomucin content of laying hens fed low-gossypol cottonseed meal(LCSM)-based diet and sought to explore the regulatory mechanism underlying the...
关键词：egg white quality low-gossypol cottonseed meal laying hen OVOMUCIN SERINE 
Integrative single-cell and bulk transcriptomes analyses reveals heterogeneity of serine-glycine-one-carbon metabolism with distinct prognoses and therapeutic vulnerabilities in HNSCC
《International Journal of Oral Science》2024年第4期711-727,共17页Lixuan Wang Rongchun Yang Yue Kong Jing Zhou Yingyao Chen Rui Li Chuwen Chen Xinran Tang Xiaobing Chen Juan Xia Xijuan Chen Bin Cheng Xianyue Ren 
supported by grants from the GuangDong Basic and Applied Basic Research Foundation(No.2023A1515030121,No.2021A1515111020,No.2023A1515010246);the National Natural Science Foundation of China(No.82273148,No.82103555,No.82301086);the Science and Technology Projects in Guangzhou(No.202206080009)。
Metabolic heterogeneity plays a central role in sustaining uncontrolled cancer cell proliferation and shaping the tumor microenvironment(TME),which significantly compromises the clinical outcomes and responses to ther...
关键词：metabolism therapeutic precise 
Essentiality of SLC7A11-mediated nonessential amino acids in MASLD被引量：2
《Science Bulletin》2024年第23期3700-3716,共17页Jie Shen Enjun Xie Shuying Shen Zijun Song Xiaopeng Li Fudi Wang Junxia Min 
supported by research grants from the National Natural Science Foundation of China(82471593 to Junxia Min,and 32330047 and 31930057 to Fudi Wang)。
Metabolic dysfunction-associated steatotic liver disease(MASLD)remains a rapidly growing global health burden.Here,we report that the nonessential amino acid(NEAA)transporter SLC7A11 plays a key role in MASLD.In patie...
关键词：SLC7A11 MASLD Serine synthesis Ferroptosis NAFLD 
Targeting SRSF10 might inhibit M2 macrophage polarization and potentiate anti-PD-1 therapy in hepatocellular carcinoma
《Cancer Communications》2024年第11期1231-1260,共30页Jialiang Cai Lina Song Feng Zhang Suiyi WuGuiqi Zhu Peiling Zhang Shiping Chen Junxian Du Biao Wang Yufan Cai Yi Yang Jinglei Wan Jian Zhou Jia Fan Zhi Dai 
supported by the National Natural Science Foundation of China(No.82372946 and No.82072670);the 12 Leading Project of the Science and Technology Committee of Shanghai Municipality(No.21Y21900100);the Project of Shanghai Municipal Health Commission(No.202140269).
Background:The efficacy of immune checkpoint blockade therapy in patients with hepatocellular carcinoma(HCC)remains poor.Although serine-and arginine-rich splicing factor(SRSF)family members play crucial roles in tumo...
关键词：GLYCOLYSIS Histone lactylation Immune checkpoint blockade Serine and arginine rich splicing factor 10 Tumor-Associated Macrophage 
Author Correction:ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH/PSAT1/serine metabolic pathway
《Acta Pharmacologica Sinica》2024年第11期2450-2451,共2页Sha Li Hong Yang Wan Li Jin-yi Liu Li-wen Ren Yi-hui Yang Bin-bin Ge Yi-zhi Zhang Wei-qi Fu Xiang-jin Zheng Guan-hua Du Jin-hua Wang 
Correction to:Acta Pharmacologica Sinica(2022)43:2709-2722;https://doi.org/10.1038/s41401-022-00894-7,published online 30 March 2022 The authors would like to apologize for the errors in the previously published image...
关键词：checked FIGURES FUSED 
大豆GmRSZ21基因克隆及表达分析
《农业生物技术学报》2024年第9期1971-1981,共11页杜梦雪 王德颖 李婧御 门庆美 贺芸 孟令志 郭尚敬 
山东省自然科学基金(K22LB56);大学生创新创业计划(2210447021);聊城大学博士科研启动基金(318052165)。
SR (serine/arginine-rich)蛋白家族是植物中一类关键调控因子,广泛参与植物生长发育的各个时期,并且能够响应非生物胁迫。本研究以栽培大豆(Glycine max)为对象,克隆了RSZ (Zn-knuckles-type arginine/serine-rich protein)亚家族的GmR...
关键词：大豆 非生物胁迫 基因克隆 生物信息学分析 RSZ21(Zn-knuckles-type arginine/serine-rich protein) 
GWAS unravels acid phosphatase ACP2 as a photosynthesis regulator under phosphate starvation conditions through modulating serine metabolism in rice
《Plant Communications》2024年第7期106-119,共14页Sushuang Liu Zhan Xu Jemaa Essemine Yanmin Liu Chundong Liu Feixue Zhang Zubair Iqbal Mingnan Qu 
supported by the National Natural Science Foundation of China(32170245,32260447);Natural Science Foundation of Zhejiang Province(LQ20C130003);Sanya Yazhou Bay Science and Technology City(SCKJ-JYRC-2022-04);Scientific Research Fund of Zhejiang Provincial Education Department(YZ0Z145972);Huzhou Public Welfare Application Research Project(2021GZ26);National Training Programs of Innovation and Entrepreneurship for Undergraduates(2022hzxy019);Guangzhou Science and Technology Planning Project(202201010790).
Inorganic phosphorus(Pi)deficiency significantly impacts plant growth,development,and photosynthetic efficiency.This study evaluated 206 rice accessions from a MiniCore population under both Pi-sufficient(Pi^(+))and P...
关键词：phosphate starvation GWAS photosynthetic adaption photosynthetic phosphate use efficiency genetic variation SNP RICE 
Dietary nutrients involved in one-carbon metabolism and colorectal cancer risk
《LabMed Discovery》2024年第2期27-38,共12页Lin Deng Yu-chan Huang-fu Yan-hui Ma 
supported by the program for Shanghai Rising Stars of Youth Medical Talents-Clinical Laboratory Practitioner Program of China(No.[2021]99).
Objective:Colorectal cancer(CRC),a common malignant tumor of the digestive tract,poses a worldwide threat to human health.Methods:This study conducted a narrative literature review to assess and provide perspectives o...
关键词：Colorectal cancer One-carbon metabolism Folate B vitamin METHIONINE SERINE 
Targeting PHGDH reverses the immunosuppressive phenotype of tumor-associated macrophages throughα-ketoglutarate and mTORC1 signaling被引量：2
《Cellular & Molecular Immunology》2024年第5期448-465,共18页Zhengnan Cai Wan Li Sonja Hager Jayne Louise Wilson Leila Afjehi-Sadat Elke HHeiss Thomas Weichhart Petra Heffeter Wolfram Weckwerth 
Phosphoglycerate dehydrogenase(PHGDH)has emerged as a crucial factor in macromolecule synthesis,neutralizing oxidative stress,and regulating methylation reactions in cancer cells,lymphocytes,and endothelial cells.Howe...
关键词：PHGDH de novo serine synthesis Α-KETOGLUTARATE mTORC1 protumorigenic tumor-associated macrophages metabolomics 
全选清除导出
共14页<12345678910>
检索报告 对象比较 聚类工具 使用帮助 返回顶部