覆膜支架置入联合放射治疗在中晚期食管癌治疗中的临床观察  

Clinical observation of the middle-late patients with esophageal cancer to perform esophageal stent placement and radiation therapy

作　　者：胥雄阳[1] 赵平宗 蒋丽琳[1] 杨兴平[1] 郭凤英[1] 贾碧慧 

机构地区：[1]四川省广元市第一人民医院消化内科,628017 [2]四川省广元市第一人民医院放射治疗科,628017

出　　处：《重庆医学》2015年第25期3542-3544,共3页Chongqing medicine

摘　　要：目的探讨食管覆膜支架置入联合放射治疗对中晚期食管癌治疗的临床价值。方法对35例中晚期食管癌患者进行覆膜支架置入术并放射治疗(治疗组),对37例中晚期食管癌患者进行单纯放射治疗(对照组),并进行临床疗效对比观察。结果治疗组术后患者吞咽困难症状均明显缓解,坚持完成全程放射治疗32例(91.4%),无因营养状况原因导致治疗情况不能完成;放射治疗后1个月以上生存期达100.0%,6个月生存期为85.7%(30/35)。对照组放射治疗开始1周内吞咽困难症状加重或无缓解,需静脉营养支持;完成全程放射治疗23例(62.2%),发生食管气管瘘5例;放射治疗后1个月生存期为83.8%(31/37),6个月生存期为62.2%(23/37)。两组患者放射治疗耐受性及放射治疗后1、6个月生存期差异有统计学意义(均P<0.05)。结论对中晚期食管癌患者,予以食管覆膜支架置入联合放射治疗较单纯放射治疗有较好疗效。Objective To study the clinical value of esophageal stent placement with radiation therapy for the middle-late patients with esophageal cancer. Methods To perform esophageal stent placement and radiation therapy for the middle-late 35 patients,and to perform radiation therapy for the middle-late 37 patients,then observe the clinical curative effects. Results The treatment group were significantly alleviated with dysphagia symptom after operation, which 32 cases sticked the entire radiation, accounting for 91.4% ,no one can＇t complete the treatment because of nutritional status reason. Survival time of one month after radiotherapy was up to 100.0% ,and survival time of six months was 85.7% （30/35）. But the contrast group with dysphagia symptom were aggravated or no relief,and needed parenteral nutrition. There were 23 cases to complete the entire radiation, accounting for 62.2 %, and 5 cases happened esophageal tracheal fistula. Survival time of one month after radiotherapy was 83.8 % （31/37）, and survival time of six months was 62.2 % （23/37）. Two groups of cases in radiotherapy resistance difference was statistically significant,one month and six months of survival time were statistically significant （all P〈0.05）. Conclusion Esophageal stent placement with radiotherapy is more efficient than only radiation therapy to the middle-late patients with esophageal cancer.

关 键 词：食管肿瘤 食管支架 放射治疗 

分 类 号：R735.1[医药卫生—肿瘤]