纳米抗体靶向治疗胃癌的研究进展  

Nanobodies for targeted treatment of gastric cancer

作　　者：刘芳腾 欧阳喜[1] 张官平[1] 罗洪亮[1] 

机构地区：[1]南昌大学第二附属医院胃肠外科,江西省南昌市330000

出　　处：《世界华人消化杂志》2015年第23期3714-3719,共6页World Chinese Journal of Digestology

摘　　要：随着近年来单克隆抗体靶向治疗药物的研发和临床应用.胃癌在治疗上取得了一些成果,但由于其制备相对复杂、价格较贵等原因,应用范围受到一定限制.而纳米抗体的出现,带来了常规分子靶向治疗药物所不具有的优势,其分子量小,结构功能性质独特,给胃癌的靶向治疗提供了新的治疗手段和研究思路.本文就具有潜在靶向治疗胃癌价值的纳米抗体,作一简介综述.With the development and application of monoclonal antibody-based targeted therapy drugs in recent years, some achievements have been made in the treatment of gastric cancer; however, because their preparation is relatively complex and expensive, their application is limited. Nanobodies have some advantages over conventional molecular targeted drugs, such as small molecular weight and unique structural features, and provide a new treatment strategy for targeted therapy of gastric cancer. In this paper, we review the nanobodies that have the potential for targeted treatment of gastric cancer.

关 键 词：胃癌 纳米抗体 靶向治疗 

分 类 号：R735.2[医药卫生—肿瘤]