早期肠内与肠外营养结合在胃癌全胃切除术后的应用效果  

Application effect of early enteral and parenteral nutrition combined on total gastrectomy for gastric cancer

作　　者：关慧慧 孙威[2] 

机构地区：[1]中国医科大学附属盛京医院普外三科,辽宁沈阳110004 [2]中国医科大学附属盛京医院胃肠营养减肥外科,辽宁沈阳110004

出　　处：《中国医药导报》2015年第26期78-81,89,共5页China Medical Herald

基　　金：辽宁省自然科学基金项目(2014021024)

摘　　要：目的：探讨早期肠内与肠外营养结合在胃癌全胃切除术后的应用效果。方法选取2013年6月-2015年2月在中国医科大学附属盛京医院行全胃切除术的胃癌患者64例，按术后营养途径分为肠内外结合组（37例）和肠外组（27例），肠内外结合组采用肠内营养和肠外营养结合营养供给及护理，肠外组采用全肠外营养及护理。比较两组患者术后7d的营养情况。结果与术前比较，肠内外结合组术后7d体重降低，但差异无统计学意义（P〉0.05），肠外组术后7 d体重显著降低，差异有统计学意义（P〈0.05），术后两组比较差异无统计学意义（P〉0.05）；肠内外结合组术后7 d血清白蛋白和血红蛋白含量较术前明显升高（P〈0.05），并明显高于肠外组（P〈0.05）。术后肠内外结合组排气时间、排便时间和住院时间与肠外组比较明显缩短，差异有统计学意义（P〈0.05）；两组经口进食时间差异无统计学意义（P〉0.05）。两组术后并发症发生率差异无统计学意义（P〉0.05）。结论早期肠内与肠外营养结合较肠外营养更有利于提高胃癌全胃切除术后患者营养状态，促进肠道功能恢复。Objective To investigate the application effect of early enteral and parenteral nutrition combined on gastric cancer patients with total gastrectomy. Methods From June 2013 to February 2015, in Shengjing Hospital Affiliated to China Medical University, 64 patients with gastric cancer underwent gastrectomy were selected, according to postopera-tive enteral nutrition combined approach, they were divided into enteral and parenteral combined group （37 cases） and parenteral group （27 cases）, patients in enteral and parenteral combined group were given enteral and parenteral nutri-tion combined nutrition and nursing, patients in parenteral group were given total parenteral nutrition and nursing. The nutrient status of patients in two groups after surgery 7 days were compared. Results After surgery 7 days, compared with before the surgery, the body weight in enteral and parenteral combined group reduced, but the difference was not statistically significant （P〉0.05）, the body weight in parenteral group significantly reduced, the difference was statisti-cally significant （P0.05）;serum albumin and hemoglobin in enteral and parenteral combined group significantly increased （P〈0.05）, and these were higher than those in parenteral group （P〈0.05）. Exhaust time, defecation time and hospital stays in enteral and parenteral combined group were less than those in parenteral group, the differences were statistically significant （P 0.05）. Conclusion Compared with parenteral nutrition, Early enteral combined with parenteral nutrition is benefi-cial to improve the nutritional status of patients with gastric cancer after total gastrectomy, and promote recovery of bowel function.

关 键 词：胃癌 肠内营养 全胃切除术 

分 类 号：R735.2[医药卫生—肿瘤]