支撑喉镜CO_2激光手术治疗喉癌的临床研究  

A clinical study on the laryngoscopic CO_2 laser surgery in the treatment of hypopharyngeal carcinoma

作　　者：彭峰[1] 莫宋平[1] 陈振清[1] 杨礼明[1] 

机构地区：[1]广东省肇庆市第一人民医院耳鼻喉科,526021

出　　处：《白求恩医学杂志》2015年第4期361-363,共3页Journal of Bethune Medical Science

摘　　要：目的探讨支撑喉镜CO2激光手术治疗喉癌的临床效果。方法将96例喉癌患者随机分为两组,各48例。观察组给予支撑喉镜CO2激光手术治疗,对照组给予气管切开喉显微镜切除术治疗。术后10 d,观察患者饮食情况;术后随访1年,6个月评定发音情况,1年评定复发率及生存率。结果术后10 d,观察组正常饮食率高于对照组(P<0.01);术后6个月,观察组嘶哑发生率低于对照组(P<0.05)。随访1年,两组患者生存率比较,差异无统计学意义(P>0.05);观察组复发率低于对照组(P<0.05)。结论支撑喉镜CO2激光手术治疗喉癌有助于提高患者饮食及语言功能,达到开放治疗生存率,且降低复发率,值得临床推广应用。Objective To investigate the effect of laryngoscopic CO2 laser surgery in treatment of laryngopharyngeal cancer. Methods Ninety-six cases of hypopharyngeal cancer were randomly divided into observation group and control group with 48 cases in each group. The observation group underwent laryngoscope CO2 laser surgical treatment, the control group underwent tracheotomy treat- ment. The postoperative diet within 10 days was observed and patients were followed up for 1 year and sound assessment was made within 6 months and assessment of recurrence and survival were made within 1 year. Results After 10 days, the normal diet rate of ob- servation group was higher than that of the control group（ P 〈0.01 ）. Six months after operation,the incidence rate of hoarseness of ob- servation group was lower than that of control group（ P 〈0.05）. 1 year after operation,survival rates of the two groups showed no sig- nificant difference （ P 〉 O. 05 ） ,but the recurrence rate in the observation group was lower than that of the control group（ P 〈 O. 05）. Conclusion The laryngoscopic COz laser operation in treatment of open throat cancer can improve dieting and language functions, in- crease survival rate and reduce recurrence rate ,which is worthy of promotion.

关 键 词：支撑喉镜 CO2激光 喉癌 气管切开 

分 类 号：R739.65[医药卫生—肿瘤]