我院质子泵抑制剂临床应用的合理性分析  

Rationality Analysis of Clinical Use of Proton Pump Inhibitors in Our Hospital

作　　者：邓健浩[1] 修连喜[1] 林素珍[1] 廖炎平[1] 

机构地区：[1]福建省龙岩市第二医院药学部,福建龙岩364000

出　　处：《中国执业药师》2015年第9期10-14,共5页China Licensed Pharmacist

摘　　要：目的:调查了解我院住院患者中质子泵抑制剂使用的合理性。方法:制定我院质子泵抑制剂的临床应用指导原则,随机抽取本院2014年1-12月的住院患者病历744份,依据指导原则进行分析评价,并对不合理的处方进行讨论。结果:744份病历中,不合理病历共320份,占43.01%,不合理的原因分别是给药途径、无使用指征、疗程偏长、用法用量、重复用药和药物相互作用,所占比例依次为33.75%,30.62%,16.25%,10.00%,5.00%,4.38%。结论:质子泵抑制剂在我院临床应用上不甚合理,为了节约医疗成本和进一步提高用药水平,还需要考虑给药途径、使用指征、疗程偏长、用法用量、重复用药和药物相互作用等多方面的因素。Objective ：To investigate the rationality of the use of proton pump inhibitors（PPIs） in the inpatients of our hospital. Methods ：The guiding principle of clinical application of proton pump inhibitors in our hospital was established. About 744 medical records of inpatients were randomly selected from January to December in 2014.The analysis and evaluation were made according to the guiding principle and the unreasonable prescriptions were discussed. Results ：Of 744 medical records, 320 of them was found unreasonable, accounting for 43.01%, which mainly reflected in the following aspects such as the route of administration, non-indicated use of drugs, long course of treatment, usage and dosage, repeated use of drugs and drug interactions, with the proportion of 33.75%,30.62%, 16.25%, 10.00%, 5.00% and 4.38% respectively. Conclusion ：The clinical use of PPI in our hospital was irrational. In order to reduce the medical cost and further improve the level of rational drug use, considerations should be given to the above mentioned factors.

关 键 词：质子泵抑制剂 合理性分析 处方点评 

分 类 号：R573.1[医药卫生—消化系统]