氟化物涂膜预防农村地区儿童未建第一恒磨牙龋  

Effect of fluoride varnish on caries prevention of partially erupted first permanent molars in rural areas

作　　者：袁雪青[1] 罗伟[1] 陈晓英[1] 

机构地区：[1]广州市花都区胡忠医院口腔科,510800

出　　处：《中华口腔医学研究杂志（电子版）》2015年第4期46-49,共4页Chinese Journal of Stomatological Research(Electronic Edition)

基　　金：广州市花都区科技计划(13HDWS-044)

摘　　要：目的：探讨氟化物涂膜在预防农村地区儿童未建第一恒磨牙龋病中的临床效果。方法运用简单随机抽样方法选取广州市花都区农村地区6-7岁一年级儿童476人,共1462颗未建第一恒磨牙纳入研究。试验组（n=212,697颗磨牙）两年内每半年予1次牙面涂布氟化物涂膜（多乐氟？）,共计5次。对照组（n=264,765颗磨牙）牙面不做涂氟处理。试验开始后每半年复查两组儿童的龋病发病情况。结果6个月后两组儿童第一恒磨牙龋病发病率、龋面均之间差异无统计学意义（P 发病率=1.000；t 龋面均=0.005,P 龋面均=0.996）。12个月后两组儿童第一恒磨牙龋病发病率、龋面均之间差异无统计学意义（χ^2发病率=1.489,P 发病率=0.222；t 龋面均=1.417,P 龋面均=0.157）。24个月后两组儿童第一恒磨牙龋病发病率、龋面均之间的差异扩大且差异均具有统计学意义（χ^2发病率=11.645,P 发病率=0.001；t 龋面均=3.408,P 龋面均=0.001）。结论氟化物涂膜能够有效预防农村地区儿童未建第一恒磨牙龋的发生,值得临床推广应用。Objective To explore the clinical effect of fluoride varnish on caries prevention of partially erupted first permanent molars in rural areas. Methods The sample included 476 children aged 6-7 years old based on simple random sampling, with a total of 1462 partially erupted first permanent molars. The children were randomly divided into test group （n=212, 697 molars） and control group （n=264, 765 molars）. The test group was semiannually applied with fluoride varnish （Duraphat ） for 5 times, and the control group was not applied in two years. All dental caries of all the children were checked every 6 months. Results No significantly statistical difference was found in the caries incidence rate or mean DMFS between 2 groups after 6 months （Pincidence rate=1.000;tmean DMFS=0.005, Pmean DMFS=0.996） or after 12 months （χ^2incidence rate=1.489, Pincidence rate=0.222; tmean DMFS=1.417, Pmean DMFS=0.157）. The caries incidence rate and mean DMFS of test group were significantly lower than those of control group （χ^2incidence rate=11.645, Pincidence rate=0.001; tmean DMFS=3.408, Pmean DMFS=0.001） after 24 months. Conclusion Application of fluoride varnish for the partially erupted first permanent molars in rural areas can effectively reduce the incidence rate of caries, which was worth being popularized in clinic.

关 键 词：氟化物 外用 磨牙 龋齿 

分 类 号：R788.1[医药卫生—口腔医学]