不同产地差不嘎蒿的质量对比研究  

Study on quality contrast of Artemisia halodendron Turcz. from different habitats

作　　者：王琰[1] 刘辉 辛艳 黄胜阳[1] 周海燕 

机构地区：[1]北京工业大学生命科学与生物工程学院,北京100124 [2]亚宝药业集团股份有限公司,山西风陵渡044602

出　　处：《中国民族民间医药》2015年第17期27-30,共4页Chinese Journal of Ethnomedicine and Ethnopharmacy

摘　　要：目的:考察不同产地差不嘎蒿药材的各项质量指标,为其质量标准建立及优质产地的筛选提供一定的实验依据。方法:采用HPLC法,流动相:乙腈-0.2%甲酸水(35∶65)流量:0.8ml/min;检测波长:288nm;柱温:30℃,测定指标性成分异樱花素、圣草酚-7-甲醚的含量;按照2010年版《中国药典》(一部)附录方法测定其醇溶性浸出物、水分、杂质、灰分含量及其酸败度,综合评定药材质量。结果:不同产地的药材之间有一定的差异,其中异樱花素、圣草酚-7-甲醚含量差异较为明显,水分随保藏年份的增加而减少,其他项的差异保持在一定范围内。结论:不同产地的差不嘎蒿药材的质量有所不同,内蒙古自治区赤峰市可作为优质种源。Objective Study the quality indicators of Artemisia halodendron Turcz.In different areas,to provide some academic basis for quality criterion and origin select of Artemisia halodendron.Method The methods of HPLC （mobile phase of acetonitrile-0.2% formic acid water （35：65）;The flow rate was 0.8 ml/min,the detection wavelength was 288 nm,column temperature 30℃）was used to determine the content of the signature ingredients -Isosakuranetin and Eriodictyol -7 -methyl ether.According to the 2010 pharmacopoeia appendix method for determining the ethanol - soluble,moisture,impurities,ash content and its degree of rancidity.To evaluate the quality of Artemisia halodendron in a comprehensive way.Results There are many differences between all the medicines,especially the content of Isosakuranetin and Eriodictyol -7 -methyl ether .Moisture content decreased with the increase of the preservation time,and other quality indexs remain within a certain range of differences.Conclusion The content of chemical com-positions in Artemisia halodendron from different place has a significant difference and and Artemisia halodendron in Chifeng,Inner Mongolia could be used as a high quality germplasm.

关 键 词：差不嘎蒿 不同产地 质量对比 异樱花素 圣草酚-7-甲醚 

分 类 号：R284.11[医药卫生—中药学]