CPP-ACP治疗正畸后釉质白斑的临床疗效评价  

The Clinical Efficacy Evaluation of CPP-ACP on White Enamel after Orthodontic Treatment

作　　者：唐璐[1] 李宇[1] 

机构地区：[1]成都大学附属医院口腔科,成都610081

出　　处：《成都医学院学报》2015年第4期442-444,共3页Journal of Chengdu Medical College

基　　金：四川省卫生厅基金资助项目(No:110091)

摘　　要：目的评价酪蛋白磷酸多肽-无定型磷酸钙(casein phosphopeptide-amorphic calcium phosphate,CPPACP,GC护牙素)对正畸治疗所致牙釉质白斑再矿化的临床疗效。方法选取正畸治疗结束后多颗牙出现釉质白斑的患者20例,随机分为安慰剂组(A组)和GC护牙素组(B组),每组10例。拍摄治疗前和治疗后的牙牙合照片,观察牙釉质白斑的变化情况,计算釉质脱矿指数(EDI),并进行评价。结果两组治疗后EDI均低于治疗前,差异有统计学意义(P<0.001)。B组治疗前后EDI差值大于A组,两组相比差异有统计学意义(P<0.001)。结论CPP-ACP对正畸所致牙釉质白斑的再矿化治疗有效。Objective To evaluate the clinical efficacy of CPP-ACP（casein phosphopeptide-amorphous calcium phosphate） in treating white enamel re-mineralization caused by orthodontic treatment. Methods 20 patients appearing teeth enamel white spots on several teeth after the orthodontic treatment were randomly divided into placebo group A（n= 10） and CPP-ACP group B（n=10）. Photos of dental occlusion were taken before and after treatment to observe the changes of enamel white,calculate the EDI（enamel demineralization index） for evaluation. Results The EDI after treatment of both groups were lower than before treatment, the difference of which was statistically significant（P〈0. 001）. The EDI change（before-after） of group B was larger than that of group A, the difference of which was statistically significant（P〈0. 001）. Conclusion CPP-ACP is efficient in treating white enamel re-mineralization caused by orthodontic treatment.

关 键 词：酪蛋白磷酸多肽-无定型磷酸钙 正畸牙釉质白斑 再矿化 

分 类 号：R783.5[医药卫生—口腔医学]