低模量钛合金表面水热法制备含银二氧化钛抗菌薄膜  

Hydrothermal Preparation of Antibacterial Ag-containing TiO_2 Film on a Low-modulus Titanium Alloy

作　　者：李红伟[1] 李雯[1] 付涛[2] 杨水云[2] 

机构地区：[1]长安大学,西安710064 [2]西安交通大学,西安710049

出　　处：《表面技术》2015年第9期50-55,共6页Surface Technology

基　　金：国家自然科学基金(50901058);中央高校基本科研业务费专项资金资助(CHD2011JC001)~~

摘　　要：目的提高医用低模量近β型TLM(Ti-25Nb-3Zr-2Sn-3Mo)钛合金的抗菌性能。方法在200℃条件下,在硝酸银溶液中对TLM合金分别进行12,24 h水热处理,在其表面制备含银Ti O2抗菌薄膜。通过SEM,XRD,XPS等表征薄膜的微观结构及状态。以去离子水水热处理TLM合金作为参照,比较薄膜的亲水性,并采用抑菌圈法研究其抗菌性能。结果 SEM,XRD及XPS分析表明,水热处理后,TLM合金表面形成了Ti O2纳米晶粒组成的薄膜,薄膜中的钛和铌分别以Ti O2和Nb2O5形式存在,银以金属态存在。接触角测试结果表明,水热处理试样表面具有良好的光致亲水性,紫外光照射30 min后,水接触角从108°降低到10°以下。抗菌实验中,水热处理试样在对大肠杆菌和金黄葡萄球菌培养24 h后,产生了明显的抑菌圈,相比之下,对金黄葡萄球菌的抑菌圈较宽。结论硝酸银溶液水热法在医用钛合金表面可以合成含银Ti O2薄膜,具有工艺简便、处理温度低、抗菌效果明显等优点。Objective To improve the antimicrobial properties of near β-type biomedical titanium alloy TLM（ Ti-25Nb-3Zr-2Sn-3Mo） with low modulus. Methods TLM alloy was hydrothermally treated in silver nitrate solution at 200 ℃ with Ag NO3 solution for12 h and 24 h respectively to prepare antibacterial Ag-containing Ti O2 film on its surface. The microstructure and status of the film were characterized by SEM,XRD and XPS. Using the TLM alloy hydrothermally treated in deionized water as the control,the hydrophilicity of the film was compared,and the antimicrobial properties were studied using the inhibition zone method. Results SEM,XRD and XPS analyses showed that the film consisting of Ti O2 nanocrystals was formed on the surface of TLM alloy after the hydrothermal treatment. X-ray photoelectron spectroscopy analysis illustrated that Ti and Nb on sample surface existed as Ti O2 and Nb2O5respectively,and Ag was in the metallic form. Contact angle measurement indicated that the treated sample had good photoinduced hydrophilicity,and the contact angle decreased from 108° to below 10° after 30 min of UV irradiation. In the antibacterial test,obvious inhibition zones against E. coli and S. aureus were observed for the treated sample after 24 h culture,and the inhibition zone was wider against S. aureus. Conclusion Through hydrothermal treatment at 200 ℃ with 10 mmol / L of Ag NO3 solution,Ag-containing Ti O2 film with antimicrobial properties could be synthesized. The hydrothermal method to prepare Ag-containing Ti O2 film in medical titanium alloy has the merits of easy operation,low processing temperature,evident antibacterial effect,etc.

关 键 词：医用钛合金 水热处理 二氧化钛 纳米银 抗菌薄膜 

分 类 号：TG174.44[金属学及工艺—金属表面处理]