浅析胆胃康胶囊治疗胆汁反流性胃炎的临床观察  

Clinical Observation of Bile Reflux Gastritis Treated with Danweikang Capsules

作　　者：杨洪英 仝瑞民 段复华 周全 余泽云[2] 

机构地区：[1]昆明友谊医院,云南昆明650031 [2]云南省中医医院,云南昆明650031

出　　处：《世界中西医结合杂志》2015年第3期398-400,426,共4页World Journal of Integrated Traditional and Western Medicine

摘　　要：目的对胆胃康胶囊治疗胆汁反流性胃炎的临床有效性进行分析,并考察其安全性。方法使用胆胃康胶囊与荆花胃康胶囊对照治疗,对胁肋疼痛、胃脘痛、呕吐、胃反、口苦烧灼症进行了临床对照研究。结果胆胃康胶囊治疗胆汁反流性胃炎的有效率为92.7%,荆花胃康胶囊有效率为73.9%,两组比较,Z=7.452,P=0.000。胆胃康组治疗前后比较,WBC平均下降1.62×1012个/L,t=3.647,P=0.001。N平均下降17.04个百分点,t=6.254,P=0.000。B超检查,阴性率51.1%,χ2=228.593,P=0.000。胃镜检查,胃黏膜炎症分级:0、+级分别增加46例、34例,++、+++级分别减少1例、79例。Z=8.456,P=0.000。结论从远期疗效看,胆胃康胶囊具有多层面、靶点治疗胆汁反流性胃炎的优势,其作用优于荆花胃康胶囊。Objective To analyze the clinical effectiveness on bile reflux gastritis treated with danweikang capsules and investigate its safety. Methods Danweikang capsules and jinhuaweikang capsules were taken for the clinical controlled study in treatment of hypochondriac pain,epigastric pain,vomiting,acid reflex,bitter taste in the mouth and burning sensation in the stomach. Results The effective rate of danweikang capsules was 92. 7% in treatment of bile reflux gastritis and that of jinhuaweikang capsules was73. 9%. In comparison of the two groups,Z = 7. 452 and P = 0. 000. In danweikang group,before and after treatment,WBC was reduced to 1. 62 × 1012 cells / L averagely,t = 3. 649,P = 0. 001. N was reduced by17. 04% averagely,t = 6. 254,P = 0. 000. In ultrasonic B test,the negative rate was 51. 1%,χ2= 228. 593,P= 0. 000. In gastroscopy,for gastric mucosa inflammation grading： 46 cases and 34 cases were graded as 0and ＋ respectively,and 1 case and 79 cases were graded as ＋＋ and ＋＋＋. Z = 8. 456,P = 0. 000. Conclusion For the long- term efficacy,danweikang capsules present the multiple and target- point advantages in treatment of bile reflux gastritis and the action is better than jinhuaweikang capsules.

关 键 词：胆胃康胶囊 胆汁反流性胃炎 临床安全性和有效性评价 

分 类 号：R573.34[医药卫生—消化系统]