嗅沟脑膜瘤的临床特征及其手术治疗  

Clinical features and microsurgical treatment of olfactory groove meningioma

作　　者：王成俊[1] 李冬梅 邱明[1] 孙剑[1] 朱海波[1] 毛更生[1] 

机构地区：[1]武警总医院神经血管外科,北京100039

出　　处：《中国微侵袭神经外科杂志》2015年第9期405-407,共3页Chinese Journal of Minimally Invasive Neurosurgery

摘　　要：目的探讨嗅沟脑膜瘤的临床特征及其手术治疗策略。方法回顾性分析20例嗅沟脑膜瘤病人的临床资料,并复习相关文献。所有病人行手术治疗,翼点入路5例,额外侧入路15例。采用Karnofsky评分法评估病人术后生活质量。结果肿瘤全切除17例（SimpsonⅠ级切除2例,Ⅱ级切除15例）,近全切除3例。术后出现颅内感染3例,肺部感染1例,经对症治疗后康复出院。手术无死亡病例。术后随访3个月~4年,平均23个月,均恢复良好。结论选择恰当手术入路,应用娴熟的显微外科技术对提高嗅沟脑膜瘤手术效果及改善病人预后有重要关系。Objective To investigate the clinical characteristics and surgical strategy of olfactory groove meningioma. Methods Clinical data of 20 patients with olfactory groove meningioma were analyzed retrospectively and relevant literatures were reviewed. All the patients received surgery, including via pterional approach in 5 patients and via frontolateral approach in 15. Karnofsky scale was used to evaluate the postoperative life quality of all the patients. Results Gross total tumor resection was achieved in 17 patients,including Simpson grade Ⅰ in 2 patients and Simpson grade Ⅱ in 15, subtotal resection in 3. Postoperative intracranial infection was observed in 3 patients and pulmonary infection in 1, who recovered well after rehabilitation. There was no death related to surgery. All the patients were followed up for 3 month to 4 years with a mean period of 23 months and recovered well. Conclusion The proper surgical approach and skillful microsurgical techniques can improve the efficacy and prognosis in the patients with olfactory groove meningioma.

关 键 词：脑膜瘤 嗅沟 入路 翼点 入路 额外侧 

分 类 号：R739.45[医药卫生—肿瘤]