Müller细胞相关因子在视网膜光凝术后修复机制中的作用  

Roles of Müller cell related cytokines in repairment after retinal photocoagulation

作　　者：郑磊[1] 温佳敏 张福燕[2] 

机构地区：[1]中山大学中山眼科中心,眼科学国家重点实验室,广州510060 [2]贵州医科大学附属医院眼科,贵州医科大学医学科学研究所,贵阳550004

出　　处：《国际眼科纵览》2015年第4期270-273,共4页International Review of Ophthalmology

基　　金：贵州省科技攻关项目（黔科合SY字[2011]3009）;贵州省科学技术基金（黔科合J字[2008]2160）

摘　　要：视网膜光凝术被认为是治疗眼底疾病的有效措施，但也容易引起邻近视网膜组织的损伤。Müller细胞在视网膜多种病理损伤后可以通过产生相关细胞因子（如中间丝蛋白、细胞周期蛋白、热休克蛋白和睫状神经营养因子等）发挥内源性保护效应，并参与光凝斑修复及视网膜瘢痕形成，与光凝术后的视野损失及视力保留密切相关。Retinal photocoagulation is considered to be an effective measure for treating fundus dis- eases, but it also easy to cause the injury of adjacent retinal tissue. Mailer cells play the protective effect by producing related cytokines （such as intermediate filament protein, cyelin, heat shock protain, and ciliary neurotrophic factor） after retinal injury, and participate in the repairment of retinal spots and scar formation. It＇ s also closely linked to the loss of visual field and visual retention after retinal photoeoagulation.

关 键 词：视网膜光凝术 MÜLLER细胞 细胞因子 修复机制 

分 类 号：R774.1[医药卫生—眼科]