20例胃小细胞癌的临床分析  

Clinical Analysis on 20 cases with Gastric Small Cell Carcinoma

作　　者：邓文英 许勇飞 李宁 罗素霞 

机构地区：[1]郑州大学附属肿瘤医院,河南郑州450008

出　　处：《肿瘤学杂志》2015年第9期734-736,共3页Journal of Chinese Oncology

摘　　要：[目的]探讨胃小细胞癌的临床特点、临床诊断、治疗方法及预后。[方法]回顾性分析20例胃小细胞癌患者的临床资料。[结果]20例患者中,17例行手术治疗,其中13例行根治性肿瘤切除术,4例行姑息性手术;3例行单纯化疗。全组患者中位生存时间为11个月,1、2、3年生存率分别为60.1%、26.2%和12.7%。患者的预后与肿瘤分期、有无淋巴结转移和手术根治程度有关(P<0.05),而与年龄、性别无关(P>0.05)。[结论]胃小细胞癌是胃恶性肿瘤中的罕见病理类型,恶性程度高,病情进展迅速,治疗方法以手术、化疗、放疗为主,总体疗效不佳。[Purpose] To investigate the clinical characteristics,diagnosis,treatment and prognosis of gastric small cell carcinoma. [Methods] Clinical data of 20 cases with gastric small cell carcinoma were analyzed retrospectively. [Results] Of 20 cases,17 cases underwent surgical treatment,including radical resection in 13 cases,palliative surgery in 4 cases,and chemotherapy alone in 3 cases. The overall median survival was 11 months,and 1-,2-,and 3-year survival rates were 60.1%,26.2% and 12.7% respectively. The prognosis of patients related to tumor staging,lymph node metastasis and radical grade of the operation（P〉0.05）,but not related to age and gender（P〈0.05）. [Conclusion] Gastric small cell carcinoma is a rare pathological type of gastric malignant tumor,with high aggression and rapid disease progression. Surgery,chemotherapy and radiotherapy are the common treatment methods,and the prognosis of the disease is poor.

关 键 词：胃肿瘤 小细胞癌 治疗 预后 

分 类 号：R735.2[医药卫生—肿瘤]