99m Tc-MIBI 显像鉴别甲状腺“冷结节”良恶性的临床价值  

Clinical value of 99m Tc-MIBI imaging in differentiating benign and malignant thyroid ‘cold nod-ule’

作　　者：武军[1] 张艳霞[1] 赵树强[1] 贾春生[1] 

机构地区：[1]山西医科大学附属汾阳医院医学科,032200

出　　处：《中国实用医刊》2015年第19期25-26,共2页Chinese Journal of Practical Medicine

摘　　要：目的：探讨99m Tc-MIBI 显像对甲状腺“冷结节”良、恶性诊断与鉴别诊断的临床应用价值。方法回顾性分析50例行甲状腺99m TcO -4核素显像为单个“冷结节”患者的临床资料，采取同日法或隔日法进行肿瘤阳性显像剂99m Tc-MIBI 显像，由两位经验丰富的医师进行阅片，并与病理结果相比较进行分析。结果99m Tc-MIBI 肿瘤显像诊断甲状腺恶性肿瘤的灵敏度、特异性、准确性和约登指数分别为72．2%（13/18）、81．3%（26/32）、78．0%（39/50）、0．535；阳性预测值和阴性预测值分别为0．73和0．93；阳性似然比和阴性似然比分别为4．7和0．14。结论99m Tc-MIBI 显像对甲状腺“冷结节”良恶性鉴别诊断有较大的临床应用价值。Objective To investigate the effect of 99mTc-MIBI imaging on diagnosis and differen-tial diagnosis of benign and malignant thyroid ‘cold nodule’. Methods Retrospective analyzed the clin-ical data of 50 patients whose thyroid 99mTcO -4 imaging showing a single ‘cold nodule’, and conducted positive imaging agent 99mTc-MIBI imaging in the same day or every other day. The results were reviewed by two experienced physicians and compared with pathological results. Results 99m Tc-MIBI imaging in the diagnosis of thyroid malignant tumor of sensitivity, specificity, accuracy and Youden index were 72. 2% （13 / 18）, 81. 3% （26 / 32）, 78. 0% （39 / 50）,0. 535. Positive predictive value and negative predictive value were 0. 73 and 0. 93; Positive likelihood ratio and negative likelihood ratio were 4. 7 and 0. 14 respectively. Conclusions 99mTc-MIBI imaging has great clinical value in differential diagnosis of benign and malignant thyroid ‘cold nodule’ diagnosis.

关 键 词：甲状腺 “冷结节” 临床价值 

分 类 号：R737.9[医药卫生—肿瘤]